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A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus

BACKGROUND: Cardiovascular disease is the leading cause of mortality worldwide, including in low- and middle-income countries. Cardiovascular risk assessment is essential to prevent the mortality caused by diabetes. AIM: The current study was conducted to assess the prevalence of cardiovascular risk...

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Autores principales: Sehgal, Arshiya, Sibia, RPS, Kaur, Jasleen, Bhajni, Ena, Sehgal, Vijay Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758795/
https://www.ncbi.nlm.nih.gov/pubmed/33376703
http://dx.doi.org/10.4103/ijabmr.IJABMR_45_20
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author Sehgal, Arshiya
Sibia, RPS
Kaur, Jasleen
Bhajni, Ena
Sehgal, Vijay Kumar
author_facet Sehgal, Arshiya
Sibia, RPS
Kaur, Jasleen
Bhajni, Ena
Sehgal, Vijay Kumar
author_sort Sehgal, Arshiya
collection PubMed
description BACKGROUND: Cardiovascular disease is the leading cause of mortality worldwide, including in low- and middle-income countries. Cardiovascular risk assessment is essential to prevent the mortality caused by diabetes. AIM: The current study was conducted to assess the prevalence of cardiovascular risk factors in type 2 diabetes and to compare the United Kingdom Prospective Diabetes Study (UKPDS) and World Health Organization (WHO)/International Society of Hypertension (ISH) chart in assessing cardiovascular risk score. MATERIALS AND METHODS: Cardiac risk assessments were done in fifty patients attending the medicine outpatient department in an institutional hospital after ethical clearance and taking informed consent from patients. Two assessment tools were applied on the same patient. RESULTS: Overall, 10% of people were obese (body mass index >30). Smoking was prevalent in 20% (10/50) of patients. Hypertension was observed in 60% (30/50) of patients. Raised total cholesterol (TC) was the most common lipid abnormality affecting 94% of patients. The WHO/ISH prediction charts identified 14% and 10% of patients with cardiovascular risk category <10 and 10–20, whereas the UKPDS engine predicted 24% and 38% in the same category. In high-risk categories 30–40 and >40, the WHO/ISH score predicted a higher proportion of patients (18% and 32%) than the UKPDS engine (8% and 4%, respectively). Kappa value was calculated to calculate the degree of agreement between two tools, and it was found to be 0.781 (P < 0.01). CONCLUSION: Raised TC and hypertension were the most prevalent risk factors. There was no significant discrepancy between two assessment tools in predicting cardiovascular risk score among type 2 diabetes mellitus patients in our study.
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spelling pubmed-77587952020-12-28 A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus Sehgal, Arshiya Sibia, RPS Kaur, Jasleen Bhajni, Ena Sehgal, Vijay Kumar Int J Appl Basic Med Res Original Article BACKGROUND: Cardiovascular disease is the leading cause of mortality worldwide, including in low- and middle-income countries. Cardiovascular risk assessment is essential to prevent the mortality caused by diabetes. AIM: The current study was conducted to assess the prevalence of cardiovascular risk factors in type 2 diabetes and to compare the United Kingdom Prospective Diabetes Study (UKPDS) and World Health Organization (WHO)/International Society of Hypertension (ISH) chart in assessing cardiovascular risk score. MATERIALS AND METHODS: Cardiac risk assessments were done in fifty patients attending the medicine outpatient department in an institutional hospital after ethical clearance and taking informed consent from patients. Two assessment tools were applied on the same patient. RESULTS: Overall, 10% of people were obese (body mass index >30). Smoking was prevalent in 20% (10/50) of patients. Hypertension was observed in 60% (30/50) of patients. Raised total cholesterol (TC) was the most common lipid abnormality affecting 94% of patients. The WHO/ISH prediction charts identified 14% and 10% of patients with cardiovascular risk category <10 and 10–20, whereas the UKPDS engine predicted 24% and 38% in the same category. In high-risk categories 30–40 and >40, the WHO/ISH score predicted a higher proportion of patients (18% and 32%) than the UKPDS engine (8% and 4%, respectively). Kappa value was calculated to calculate the degree of agreement between two tools, and it was found to be 0.781 (P < 0.01). CONCLUSION: Raised TC and hypertension were the most prevalent risk factors. There was no significant discrepancy between two assessment tools in predicting cardiovascular risk score among type 2 diabetes mellitus patients in our study. Wolters Kluwer - Medknow 2020 2020-10-07 /pmc/articles/PMC7758795/ /pubmed/33376703 http://dx.doi.org/10.4103/ijabmr.IJABMR_45_20 Text en Copyright: © 2020 International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Sehgal, Arshiya
Sibia, RPS
Kaur, Jasleen
Bhajni, Ena
Sehgal, Vijay Kumar
A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus
title A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus
title_full A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus
title_fullStr A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus
title_full_unstemmed A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus
title_short A Cross-Sectional Study to Evaluate Cardiovascular Risk Score in Type 2 Diabetes Mellitus
title_sort cross-sectional study to evaluate cardiovascular risk score in type 2 diabetes mellitus
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758795/
https://www.ncbi.nlm.nih.gov/pubmed/33376703
http://dx.doi.org/10.4103/ijabmr.IJABMR_45_20
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