Low intratumor heterogeneity correlates with increased response to PD-1 blockade in renal cell carcinoma

BACKGROUND: Intratumor heterogeneity (ITH) has been shown to be inversely associated with immune infiltration in several cancers including clear cell renal cell carcinoma (ccRCC), but it remains unclear whether ITH is associated with response to immunotherapy (e.g. PD-1 blockade) in ccRCC. METHODS:...

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Detalles Bibliográficos
Autores principales: Ran, Xia, Xiao, Jinyuan, Zhang, Yi, Teng, Huajing, Cheng, Fang, Chen, Huiqian, Zhang, Kaifan, Sun, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758866/
https://www.ncbi.nlm.nih.gov/pubmed/33425025
http://dx.doi.org/10.1177/1758835920977117

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