Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction

Eukaryotic SMC complexes, cohesin, condensin, and Smc5/6, use ATP hydrolysis to power a plethora of functions requiring organization and restructuring of eukaryotic chromosomes in interphase and during mitosis. The Smc5/6 mechanism of action and its activity on DNA are largely unknown. Here we purif...

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Detalles Bibliográficos
Autores principales: Gutierrez-Escribano, Pilar, Hormeño, Silvia, Madariaga-Marcos, Julene, Solé-Soler, Roger, O’Reilly, Francis J., Morris, Kyle, Aicart-Ramos, Clara, Aramayo, Ricardo, Montoya, Alex, Kramer, Holger, Rappsilber, Juri, Torres-Rosell, Jordi, Moreno-Herrero, Fernando, Aragon, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758880/
https://www.ncbi.nlm.nih.gov/pubmed/33301732
http://dx.doi.org/10.1016/j.molcel.2020.11.012

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