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Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering
[Image: see text] A three-dimensional finite element model of articular cartilage was established to explore the mechanical behavior of the repaired area under physiological compression loading. A circular vertical material and a circular inclined stacking material were fabricated, and a 3D printing...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758984/ https://www.ncbi.nlm.nih.gov/pubmed/33376878 http://dx.doi.org/10.1021/acsomega.0c04378 |
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author | Sun, Kai Li, Ruixin Li, Hui Fan, Meng Li, Hao |
author_facet | Sun, Kai Li, Ruixin Li, Hui Fan, Meng Li, Hao |
author_sort | Sun, Kai |
collection | PubMed |
description | [Image: see text] A three-dimensional finite element model of articular cartilage was established to explore the mechanical behavior of the repaired area under physiological compression loading. A circular vertical material and a circular inclined stacking material were fabricated, and a 3D printing method was employed for producing three-dimensional solids. The physical and biomechanical properties and biocompatibility were tested. The presence of cells in the circular vertically stacked scaffold significantly promoted the matrix deposition and the cell viability compared with that in the circular inclined scaffolds. The scaffolds made of the circular vertical material and the circular inclined stacking material scaffolds exhibited better overall performance. |
format | Online Article Text |
id | pubmed-7758984 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-77589842020-12-28 Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering Sun, Kai Li, Ruixin Li, Hui Fan, Meng Li, Hao ACS Omega [Image: see text] A three-dimensional finite element model of articular cartilage was established to explore the mechanical behavior of the repaired area under physiological compression loading. A circular vertical material and a circular inclined stacking material were fabricated, and a 3D printing method was employed for producing three-dimensional solids. The physical and biomechanical properties and biocompatibility were tested. The presence of cells in the circular vertically stacked scaffold significantly promoted the matrix deposition and the cell viability compared with that in the circular inclined scaffolds. The scaffolds made of the circular vertical material and the circular inclined stacking material scaffolds exhibited better overall performance. American Chemical Society 2020-12-07 /pmc/articles/PMC7758984/ /pubmed/33376878 http://dx.doi.org/10.1021/acsomega.0c04378 Text en © 2020 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes. |
spellingShingle | Sun, Kai Li, Ruixin Li, Hui Fan, Meng Li, Hao Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering |
title | Analysis and Demonstration of a Scaffold Finite Element
Model for Cartilage Tissue Engineering |
title_full | Analysis and Demonstration of a Scaffold Finite Element
Model for Cartilage Tissue Engineering |
title_fullStr | Analysis and Demonstration of a Scaffold Finite Element
Model for Cartilage Tissue Engineering |
title_full_unstemmed | Analysis and Demonstration of a Scaffold Finite Element
Model for Cartilage Tissue Engineering |
title_short | Analysis and Demonstration of a Scaffold Finite Element
Model for Cartilage Tissue Engineering |
title_sort | analysis and demonstration of a scaffold finite element
model for cartilage tissue engineering |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758984/ https://www.ncbi.nlm.nih.gov/pubmed/33376878 http://dx.doi.org/10.1021/acsomega.0c04378 |
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