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Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering

[Image: see text] A three-dimensional finite element model of articular cartilage was established to explore the mechanical behavior of the repaired area under physiological compression loading. A circular vertical material and a circular inclined stacking material were fabricated, and a 3D printing...

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Autores principales: Sun, Kai, Li, Ruixin, Li, Hui, Fan, Meng, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758984/
https://www.ncbi.nlm.nih.gov/pubmed/33376878
http://dx.doi.org/10.1021/acsomega.0c04378
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author Sun, Kai
Li, Ruixin
Li, Hui
Fan, Meng
Li, Hao
author_facet Sun, Kai
Li, Ruixin
Li, Hui
Fan, Meng
Li, Hao
author_sort Sun, Kai
collection PubMed
description [Image: see text] A three-dimensional finite element model of articular cartilage was established to explore the mechanical behavior of the repaired area under physiological compression loading. A circular vertical material and a circular inclined stacking material were fabricated, and a 3D printing method was employed for producing three-dimensional solids. The physical and biomechanical properties and biocompatibility were tested. The presence of cells in the circular vertically stacked scaffold significantly promoted the matrix deposition and the cell viability compared with that in the circular inclined scaffolds. The scaffolds made of the circular vertical material and the circular inclined stacking material scaffolds exhibited better overall performance.
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spelling pubmed-77589842020-12-28 Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering Sun, Kai Li, Ruixin Li, Hui Fan, Meng Li, Hao ACS Omega [Image: see text] A three-dimensional finite element model of articular cartilage was established to explore the mechanical behavior of the repaired area under physiological compression loading. A circular vertical material and a circular inclined stacking material were fabricated, and a 3D printing method was employed for producing three-dimensional solids. The physical and biomechanical properties and biocompatibility were tested. The presence of cells in the circular vertically stacked scaffold significantly promoted the matrix deposition and the cell viability compared with that in the circular inclined scaffolds. The scaffolds made of the circular vertical material and the circular inclined stacking material scaffolds exhibited better overall performance. American Chemical Society 2020-12-07 /pmc/articles/PMC7758984/ /pubmed/33376878 http://dx.doi.org/10.1021/acsomega.0c04378 Text en © 2020 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Sun, Kai
Li, Ruixin
Li, Hui
Fan, Meng
Li, Hao
Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering
title Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering
title_full Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering
title_fullStr Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering
title_full_unstemmed Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering
title_short Analysis and Demonstration of a Scaffold Finite Element Model for Cartilage Tissue Engineering
title_sort analysis and demonstration of a scaffold finite element model for cartilage tissue engineering
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758984/
https://www.ncbi.nlm.nih.gov/pubmed/33376878
http://dx.doi.org/10.1021/acsomega.0c04378
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