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The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia

BACKGROUND: Cicatricial alopecia (CA) is scarring alopecia due to a diverse group of disorders which destroy the hair follicle, replace it with scar tissue causing permanent hair loss. Spontaneous regrowth of hair in CA is rarely seen and thus it has a negative impact on the self-esteem of the patie...

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Autores principales: Madura, C., Vinay, N., Kusuma, M. R., Harsha, S., Chandrashekar, B. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759062/
https://www.ncbi.nlm.nih.gov/pubmed/33376285
http://dx.doi.org/10.4103/ijt.ijt_52_19
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author Madura, C.
Vinay, N.
Kusuma, M. R.
Harsha, S.
Chandrashekar, B. S.
author_facet Madura, C.
Vinay, N.
Kusuma, M. R.
Harsha, S.
Chandrashekar, B. S.
author_sort Madura, C.
collection PubMed
description BACKGROUND: Cicatricial alopecia (CA) is scarring alopecia due to a diverse group of disorders which destroy the hair follicle, replace it with scar tissue causing permanent hair loss. Spontaneous regrowth of hair in CA is rarely seen and thus it has a negative impact on the self-esteem of the patient. However, hair transplantation (HT) has emerged as an effective modality of treatment to replace lost hair for cosmetic benefit. MATERIALS AND METHODS: This was a prospective analysis of patients affected with CA, who underwent HT from January 2015 to December 2017. Demography of patients along with the duration of disease, stability, biopsy, technique of HT, number of grafts, and other procedures done were noted on a pro forma and analyzed. A test patch of HT was done in all primary CA to assess stability and few secondary CA to look for graft uptake. The patients were followed up for a year and the outcomes were graded by patient and a single observer on a 10 point scale as poor, satisfactory, good, and very good at 3, 6, and 12 months. RESULTS: A total of 50 patients with CA underwent follicular unit extraction. Majority of them were males(84%) with a male to female ratio of 5.25:1. Secondary CA was seen in majority(90%) of the study group. Moustache (56%) was the most common site affected, followed by scalp (22%), beard(14%) and eyebrow(8%). Around 38%(12 atrophic scars; 7 hypertrophic scars) underwent fractional CO2 laser/Erbium YAG laser with or without intralesional steroid injections in a stepwise manner prior to HT. Excellent-to-very good outcome was seen in 82% while 18% were lost for follow up. CONCLUSION: Scarring in CA has a significant effect on quality of life of affected patients. HT when done taking into consideration the stability of disease has good-to-excellent outcomes thus leading to a positive impact on the patient's life.
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spelling pubmed-77590622020-12-28 The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia Madura, C. Vinay, N. Kusuma, M. R. Harsha, S. Chandrashekar, B. S. Int J Trichology Original Article BACKGROUND: Cicatricial alopecia (CA) is scarring alopecia due to a diverse group of disorders which destroy the hair follicle, replace it with scar tissue causing permanent hair loss. Spontaneous regrowth of hair in CA is rarely seen and thus it has a negative impact on the self-esteem of the patient. However, hair transplantation (HT) has emerged as an effective modality of treatment to replace lost hair for cosmetic benefit. MATERIALS AND METHODS: This was a prospective analysis of patients affected with CA, who underwent HT from January 2015 to December 2017. Demography of patients along with the duration of disease, stability, biopsy, technique of HT, number of grafts, and other procedures done were noted on a pro forma and analyzed. A test patch of HT was done in all primary CA to assess stability and few secondary CA to look for graft uptake. The patients were followed up for a year and the outcomes were graded by patient and a single observer on a 10 point scale as poor, satisfactory, good, and very good at 3, 6, and 12 months. RESULTS: A total of 50 patients with CA underwent follicular unit extraction. Majority of them were males(84%) with a male to female ratio of 5.25:1. Secondary CA was seen in majority(90%) of the study group. Moustache (56%) was the most common site affected, followed by scalp (22%), beard(14%) and eyebrow(8%). Around 38%(12 atrophic scars; 7 hypertrophic scars) underwent fractional CO2 laser/Erbium YAG laser with or without intralesional steroid injections in a stepwise manner prior to HT. Excellent-to-very good outcome was seen in 82% while 18% were lost for follow up. CONCLUSION: Scarring in CA has a significant effect on quality of life of affected patients. HT when done taking into consideration the stability of disease has good-to-excellent outcomes thus leading to a positive impact on the patient's life. Wolters Kluwer - Medknow 2020 2020-09-19 /pmc/articles/PMC7759062/ /pubmed/33376285 http://dx.doi.org/10.4103/ijt.ijt_52_19 Text en Copyright: © 2020 International Journal of Trichology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Madura, C.
Vinay, N.
Kusuma, M. R.
Harsha, S.
Chandrashekar, B. S.
The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia
title The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia
title_full The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia
title_fullStr The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia
title_full_unstemmed The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia
title_short The assessment of Hair Transplantation Outcomes in Cicatricial Alopecia
title_sort assessment of hair transplantation outcomes in cicatricial alopecia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759062/
https://www.ncbi.nlm.nih.gov/pubmed/33376285
http://dx.doi.org/10.4103/ijt.ijt_52_19
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