Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo

The Democratic Republic of the Congo (DRC) has begun implementing HIV self-testing to boost the first “95” of the UNAIDS 95-95-95 targets by 2025. This study aims to assess the performance and usability of the Exacto Test HIV (Biosynex, Strasbourg, France) self-test in the lab and in the field. The...

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Autores principales: Tonen-Wolyec, Serge, Muwonga Masidi, Jérémie, Kamanga Lukusa, Luc Ferdinand, Nsiku Dikumbwa, Gaetan, Sarassoro, Angèle, Bélec, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759209/
https://www.ncbi.nlm.nih.gov/pubmed/33409330
http://dx.doi.org/10.1093/ofid/ofaa554
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author Tonen-Wolyec, Serge
Muwonga Masidi, Jérémie
Kamanga Lukusa, Luc Ferdinand
Nsiku Dikumbwa, Gaetan
Sarassoro, Angèle
Bélec, Laurent
author_facet Tonen-Wolyec, Serge
Muwonga Masidi, Jérémie
Kamanga Lukusa, Luc Ferdinand
Nsiku Dikumbwa, Gaetan
Sarassoro, Angèle
Bélec, Laurent
author_sort Tonen-Wolyec, Serge
collection PubMed
description The Democratic Republic of the Congo (DRC) has begun implementing HIV self-testing to boost the first “95” of the UNAIDS 95-95-95 targets by 2025. This study aims to assess the performance and usability of the Exacto Test HIV (Biosynex, Strasbourg, France) self-test in the lab and in the field. The Exacto Test HIV self-test demonstrated high virological performance (sensitivity, 99.6%; specificity, 100%) in the lab and in the field in the hand of untrained users (sensitivity, 100%; specificity, 98.9%). Taken together, the excellent performance and usability characteristics of the Exacto Test HIV (Biosynex) self-test make the kit a viable option for HIV self-testing in the DRC.
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spelling pubmed-77592092021-01-05 Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo Tonen-Wolyec, Serge Muwonga Masidi, Jérémie Kamanga Lukusa, Luc Ferdinand Nsiku Dikumbwa, Gaetan Sarassoro, Angèle Bélec, Laurent Open Forum Infect Dis Brief Reports The Democratic Republic of the Congo (DRC) has begun implementing HIV self-testing to boost the first “95” of the UNAIDS 95-95-95 targets by 2025. This study aims to assess the performance and usability of the Exacto Test HIV (Biosynex, Strasbourg, France) self-test in the lab and in the field. The Exacto Test HIV self-test demonstrated high virological performance (sensitivity, 99.6%; specificity, 100%) in the lab and in the field in the hand of untrained users (sensitivity, 100%; specificity, 98.9%). Taken together, the excellent performance and usability characteristics of the Exacto Test HIV (Biosynex) self-test make the kit a viable option for HIV self-testing in the DRC. Oxford University Press 2020-11-29 /pmc/articles/PMC7759209/ /pubmed/33409330 http://dx.doi.org/10.1093/ofid/ofaa554 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Tonen-Wolyec, Serge
Muwonga Masidi, Jérémie
Kamanga Lukusa, Luc Ferdinand
Nsiku Dikumbwa, Gaetan
Sarassoro, Angèle
Bélec, Laurent
Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo
title Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo
title_full Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo
title_fullStr Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo
title_full_unstemmed Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo
title_short Analytical Performance of the Exacto Test HIV Self-Test: A Cross-Sectional Field Study in the Democratic Republic of the Congo
title_sort analytical performance of the exacto test hiv self-test: a cross-sectional field study in the democratic republic of the congo
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759209/
https://www.ncbi.nlm.nih.gov/pubmed/33409330
http://dx.doi.org/10.1093/ofid/ofaa554
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