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Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months
We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 days and the second for 62 day...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Author(s). Published by Elsevier B.V.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759339/ https://www.ncbi.nlm.nih.gov/pubmed/33352320 http://dx.doi.org/10.1016/j.meegid.2020.104684 |
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| author | Abu-Raddad, Laith J. Chemaitelly, Hiam Malek, Joel A. Ahmed, Ayeda A. Mohamoud, Yasmin A. Younuskunju, Shameem Al Kanaani, Zaina Al Khal, Abdullatif Al Kuwari, Einas Butt, Adeel A. Coyle, Peter Jeremijenko, Andrew Kaleeckal, Anvar Hassan Latif, Ali Nizar Shaik, Riyazuddin Mohammad Abdul Rahim, Hanan F. Yassine, Hadi M. Al Kuwari, Mohamed G. Al Romaihi, Hamad Eid Al-Thani, Mohamed H. Bertollini, Roberto |
| author_facet | Abu-Raddad, Laith J. Chemaitelly, Hiam Malek, Joel A. Ahmed, Ayeda A. Mohamoud, Yasmin A. Younuskunju, Shameem Al Kanaani, Zaina Al Khal, Abdullatif Al Kuwari, Einas Butt, Adeel A. Coyle, Peter Jeremijenko, Andrew Kaleeckal, Anvar Hassan Latif, Ali Nizar Shaik, Riyazuddin Mohammad Abdul Rahim, Hanan F. Yassine, Hadi M. Al Kuwari, Mohamed G. Al Romaihi, Hamad Eid Al-Thani, Mohamed H. Bertollini, Roberto |
| author_sort | Abu-Raddad, Laith J. |
| collection | PubMed |
| description | We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 days and the second for 62 days. Clearance of infection occurred 40 and 41 days, respectively, after development of detectable antibodies. Both cases were identified incidentally in an investigation of reinfection in a cohort of 133,266 laboratory-confirmed infected persons. |
| format | Online Article Text |
| id | pubmed-7759339 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2021 |
| publisher | The Author(s). Published by Elsevier B.V. |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-77593392020-12-28 Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months Abu-Raddad, Laith J. Chemaitelly, Hiam Malek, Joel A. Ahmed, Ayeda A. Mohamoud, Yasmin A. Younuskunju, Shameem Al Kanaani, Zaina Al Khal, Abdullatif Al Kuwari, Einas Butt, Adeel A. Coyle, Peter Jeremijenko, Andrew Kaleeckal, Anvar Hassan Latif, Ali Nizar Shaik, Riyazuddin Mohammad Abdul Rahim, Hanan F. Yassine, Hadi M. Al Kuwari, Mohamed G. Al Romaihi, Hamad Eid Al-Thani, Mohamed H. Bertollini, Roberto Infect Genet Evol Short Communication We document two cases of viremic and prolonged active infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) where the viral genome was conserved for two months, but infection was with little or no symptoms. The first infection persisted for 80 days and the second for 62 days. Clearance of infection occurred 40 and 41 days, respectively, after development of detectable antibodies. Both cases were identified incidentally in an investigation of reinfection in a cohort of 133,266 laboratory-confirmed infected persons. The Author(s). Published by Elsevier B.V. 2021-03 2020-12-24 /pmc/articles/PMC7759339/ /pubmed/33352320 http://dx.doi.org/10.1016/j.meegid.2020.104684 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Short Communication Abu-Raddad, Laith J. Chemaitelly, Hiam Malek, Joel A. Ahmed, Ayeda A. Mohamoud, Yasmin A. Younuskunju, Shameem Al Kanaani, Zaina Al Khal, Abdullatif Al Kuwari, Einas Butt, Adeel A. Coyle, Peter Jeremijenko, Andrew Kaleeckal, Anvar Hassan Latif, Ali Nizar Shaik, Riyazuddin Mohammad Abdul Rahim, Hanan F. Yassine, Hadi M. Al Kuwari, Mohamed G. Al Romaihi, Hamad Eid Al-Thani, Mohamed H. Bertollini, Roberto Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months |
| title | Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months |
| title_full | Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months |
| title_fullStr | Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months |
| title_full_unstemmed | Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months |
| title_short | Two prolonged viremic SARS-CoV-2 infections with conserved viral genome for two months |
| title_sort | two prolonged viremic sars-cov-2 infections with conserved viral genome for two months |
| topic | Short Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759339/ https://www.ncbi.nlm.nih.gov/pubmed/33352320 http://dx.doi.org/10.1016/j.meegid.2020.104684 |
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