Cargando…

Functional implications of MIR domains in protein O-mannosylation

Protein O-mannosyltransferases (PMTs) represent a conserved family of multispanning endoplasmic reticulum membrane proteins involved in glycosylation of S/T-rich protein substrates and unfolded proteins. PMTs work as dimers and contain a luminal MIR domain with a β-trefoil fold, which is susceptive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiapparino, Antonella, Grbavac, Antonija, Jonker, Hendrik RA, Hackmann, Yvonne, Mortensen, Sofia, Zatorska, Ewa, Schott, Andrea, Stier, Gunter, Saxena, Krishna, Wild, Klemens, Schwalbe, Harald, Strahl, Sabine, Sinning, Irmgard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Structural Biology and Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759382/ https://www.ncbi.nlm.nih.gov/pubmed/33357379 http://dx.doi.org/10.7554/eLife.61189

Ejemplares similares

Structure of the complete bacterial SRP Alu domain
por: Kempf, Georg, et al.
Publicado: (2014)

The structure of Rpf2–Rrs1 explains its role in ribosome biogenesis
por: Kharde, Satyavati, et al.
Publicado: (2015)

Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction
por: Becker, Matthias M. M., et al.
Publicado: (2017)

9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments
por: Dodonova, Svetlana O, et al.
Publicado: (2017)

L11 domain rearrangement upon binding to RNA and thiostrepton studied by NMR spectroscopy
por: Jonker, Hendrik R. A., et al.
Publicado: (2007)

High-resolution NMR structure of an RNA model system: the 14-mer cUUCGg tetraloop hairpin RNA
por: Nozinovic, Senada, et al.
Publicado: (2010)

Translational Regulation of Pmt1 and Pmt2 by Bfr1 Affects Unfolded Protein O-Mannosylation
por: Castells-Ballester, Joan, et al.
Publicado: (2019)

Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction
por: Horn, Annemarie, et al.
Publicado: (2015)

Changes in the free-energy landscape of p38α MAP kinase through its canonical activation and binding events as studied by enhanced molecular dynamics simulations
por: Kuzmanic, Antonija, et al.
Publicado: (2017)

RNA gymnastics in mammalian signal recognition particle assembly
por: Wild, Klemens, et al.
Publicado: (2015)

NMR structure of the Vibrio vulnificus ribosomal protein S1 domains D3 and D4 provides insights into molecular recognition of single-stranded RNAs
por: Qureshi, Nusrat Shahin, et al.
Publicado: (2021)

cpSRP43 Is a Novel Chaperone Specific for Light-harvesting Chlorophyll a,b-binding Proteins
por: Falk, Sebastian, et al.
Publicado: (2010)

Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel
por: Basak, Sandip, et al.
Publicado: (2017)

Direct assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMR
por: Erlendsson, Simon, et al.
Publicado: (2017)

Structural basis for the complex DNA binding behavior of the plant stem cell regulator WUSCHEL
por: Sloan, Jeremy, et al.
Publicado: (2020)

Concerted removal of the Erb1–Ytm1 complex in ribosome biogenesis relies on an elaborate interface
por: Thoms, Matthias, et al.
Publicado: (2016)

Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan
por: Chang, Tao-Hsin, et al.
Publicado: (2015)

Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
por: Paulino, Cristina, et al.
Publicado: (2017)

Protein O-Mannosylation in the Murine Brain: Occurrence of Mono-O-Mannosyl Glycans and Identification of New Substrates
por: Bartels, Markus F., et al.
Publicado: (2016)

Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1
por: Iwig, Jeffrey S, et al.
Publicado: (2013)

RNA Polymerase II cluster dynamics predict mRNA output in living cells
por: Cho, Won-Ki, et al.
Publicado: (2016)

High-resolution structure of stem-loop 4 from the 5′-UTR of SARS-CoV-2 solved by solution state NMR
por: Vögele, Jennifer, et al.
Publicado: (2023)

Epithelial magnesium transport by TRPM6 is essential for prenatal development and adult survival
por: Chubanov, Vladimir, et al.
Publicado: (2016)

Fe65-PTB2 Dimerization Mimics Fe65-APP Interaction
por: Feilen, Lukas P., et al.
Publicado: (2017)

The conformational landscape of transcription intermediates involved in the regulation of the ZMP-sensing riboswitch from Thermosinus carboxydivorans
por: Binas, Oliver, et al.
Publicado: (2020)

High-resolution structures of a thermophilic eukaryotic 80S ribosome reveal atomistic details of translocation
por: Kišonaitė, Miglė, et al.
Publicado: (2022)

Structural analyses at pseudo atomic resolution of Chikungunya virus and antibodies show mechanisms of neutralization
por: Sun, Siyang, et al.
Publicado: (2013)

Building a super elongation complex for HIV
por: Hill, Christopher P, et al.
Publicado: (2013)

Mechanism for priming DNA synthesis by yeast DNA Polymerase α
por: Perera, Rajika L, et al.
Publicado: (2013)

Influenza-virus membrane fusion by cooperative fold-back of stochastically induced hemagglutinin intermediates
por: Ivanovic, Tijana, et al.
Publicado: (2013)

Direct detection pays off for electron cryo-microscopy
por: Grigorieff, Nikolaus
Publicado: (2013)

Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles
por: Bai, Xiao-chen, et al.
Publicado: (2013)

The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat
por: Schulze-Gahmen, Ursula, et al.
Publicado: (2013)

De novo modeling of the F(420)-reducing [NiFe]-hydrogenase from a methanogenic archaeon by cryo-electron microscopy
por: Mills, Deryck J, et al.
Publicado: (2013)

Myosin motors fragment and compact membrane-bound actin filaments
por: Vogel, Sven K, et al.
Publicado: (2013)

Strong inter-population cooperation leads to partner intermixing in microbial communities
por: Momeni, Babak, et al.
Publicado: (2013)

Tapered whiskers are required for active tactile sensation
por: Hires, Samuel Andrew, et al.
Publicado: (2013)

A surprising twist
por: Fakhri, Nikta, et al.
Publicado: (2014)

Encounter complexes and dimensionality reduction in protein–protein association
por: Kozakov, Dima, et al.
Publicado: (2014)

Structural basis for the assembly of the mitotic motor Kinesin-5 into bipolar tetramers
por: Scholey, Jessica E, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_1sojfbt6cmhqdde3uf5glt50ih