E. coli NF73-1 Isolated From NASH Patients Aggravates NAFLD in Mice by Translocating Into the Liver and Stimulating M1 Polarization

OBJECTIVE: The gut microbiota is associated with nonalcoholic fatty liver disease (NAFLD). We isolated the Escherichia coli strain NF73-1 from the intestines of a NASH patient and then investigated its effect and underlying mechanism. METHODS: 16S ribosomal RNA (16S rRNA) amplicon sequencing was use...

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Detalles Bibliográficos
Autores principales: Zhang, Yifan, Jiang, Weiwei, Xu, Jun, Wu, Na, Wang, Yang, Lin, Tianyu, Liu, Yun, Liu, Yulan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759485/
https://www.ncbi.nlm.nih.gov/pubmed/33363046
http://dx.doi.org/10.3389/fcimb.2020.535940

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