Blocking PDGF-CC signaling ameliorates multiple sclerosis-like neuroinflammation by inhibiting disruption of the blood–brain barrier

Disruption of blood–brain barrier (BBB) integrity is a feature of various neurological disorders. Here we found that the BBB is differently affected during the preclinical, progression and remission phase of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS)....

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Detalles Bibliográficos
Autores principales: Zeitelhofer, Manuel, Adzemovic, Milena Z., Moessinger, Christine, Stefanitsch, Christina, Strell, Carina, Muhl, Lars, Brundin, Lou, Fredriksson, Linda, Olsson, Tomas, Eriksson, Ulf, Nilsson, Ingrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759579/
https://www.ncbi.nlm.nih.gov/pubmed/33361796
http://dx.doi.org/10.1038/s41598-020-79598-z

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