Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation

We herein report four patients with desquamative esophagitis that developed one to nine days after peripheral blood stem cell transplantation (PBSCT). Three patients underwent allogeneic PBSCT for leukemia, and the other underwent autologous PBSCT for pineoblastoma. Esophagogastroduodenoscopy reveal...

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Autores principales: Iwamuro, Masaya, Ennishi, Daisuke, Matsuoka, Ken-ichi, Tanaka, Takehiro, Okanoue, Shotaro, Obayashi, Yuka, Sakae, Hiroyuki, Kawahara, Yoshiro, Okada, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759710/
https://www.ncbi.nlm.nih.gov/pubmed/32759586
http://dx.doi.org/10.2169/internalmedicine.4977-20
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author Iwamuro, Masaya
Ennishi, Daisuke
Matsuoka, Ken-ichi
Tanaka, Takehiro
Okanoue, Shotaro
Obayashi, Yuka
Sakae, Hiroyuki
Kawahara, Yoshiro
Okada, Hiroyuki
author_facet Iwamuro, Masaya
Ennishi, Daisuke
Matsuoka, Ken-ichi
Tanaka, Takehiro
Okanoue, Shotaro
Obayashi, Yuka
Sakae, Hiroyuki
Kawahara, Yoshiro
Okada, Hiroyuki
author_sort Iwamuro, Masaya
collection PubMed
description We herein report four patients with desquamative esophagitis that developed one to nine days after peripheral blood stem cell transplantation (PBSCT). Three patients underwent allogeneic PBSCT for leukemia, and the other underwent autologous PBSCT for pineoblastoma. Esophagogastroduodenoscopy revealed mucosal sloughing and fresh blood in the esophagus. Fasting and intravenous proton pump inhibitor therapy in addition to blood transfusion improved the esophageal lesions within five to seven days in three patients. These cases indicate that desquamative esophagitis can occur in patients who receive hematopoietic stem cell transplantation. Although blood transfusions may be required, it can be resolved within seven days.
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spelling pubmed-77597102020-12-31 Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation Iwamuro, Masaya Ennishi, Daisuke Matsuoka, Ken-ichi Tanaka, Takehiro Okanoue, Shotaro Obayashi, Yuka Sakae, Hiroyuki Kawahara, Yoshiro Okada, Hiroyuki Intern Med Case Report We herein report four patients with desquamative esophagitis that developed one to nine days after peripheral blood stem cell transplantation (PBSCT). Three patients underwent allogeneic PBSCT for leukemia, and the other underwent autologous PBSCT for pineoblastoma. Esophagogastroduodenoscopy revealed mucosal sloughing and fresh blood in the esophagus. Fasting and intravenous proton pump inhibitor therapy in addition to blood transfusion improved the esophageal lesions within five to seven days in three patients. These cases indicate that desquamative esophagitis can occur in patients who receive hematopoietic stem cell transplantation. Although blood transfusions may be required, it can be resolved within seven days. The Japanese Society of Internal Medicine 2020-08-04 2020-12-01 /pmc/articles/PMC7759710/ /pubmed/32759586 http://dx.doi.org/10.2169/internalmedicine.4977-20 Text en Copyright © 2020 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Iwamuro, Masaya
Ennishi, Daisuke
Matsuoka, Ken-ichi
Tanaka, Takehiro
Okanoue, Shotaro
Obayashi, Yuka
Sakae, Hiroyuki
Kawahara, Yoshiro
Okada, Hiroyuki
Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation
title Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation
title_full Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation
title_fullStr Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation
title_full_unstemmed Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation
title_short Four Cases of Desquamative Esophagitis Occurring after Hematopoietic Stem Cell Transplantation
title_sort four cases of desquamative esophagitis occurring after hematopoietic stem cell transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759710/
https://www.ncbi.nlm.nih.gov/pubmed/32759586
http://dx.doi.org/10.2169/internalmedicine.4977-20
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