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Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery

An assessment of the natural ochratoxin A (OTA) exposure of seven Martina Franca jennies was carried out by analyzing blood and milk samples collected close to and after delivery. A total of 41 and 34 blood samples were collected from jennies and foals, respectively, and analyzed by ELISA. A total o...

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Autores principales: Lippolis, Vincenzo, Asif, Shafaq, Pascale, Michelangelo, Cervellieri, Salvatore, Mancini, Erminia, Peli, Angelo, De Amicis, Ippolito, Robbe, Domenico, Minervini, Fiorenza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759822/
https://www.ncbi.nlm.nih.gov/pubmed/33271760
http://dx.doi.org/10.3390/toxins12120758
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author Lippolis, Vincenzo
Asif, Shafaq
Pascale, Michelangelo
Cervellieri, Salvatore
Mancini, Erminia
Peli, Angelo
De Amicis, Ippolito
Robbe, Domenico
Minervini, Fiorenza
author_facet Lippolis, Vincenzo
Asif, Shafaq
Pascale, Michelangelo
Cervellieri, Salvatore
Mancini, Erminia
Peli, Angelo
De Amicis, Ippolito
Robbe, Domenico
Minervini, Fiorenza
author_sort Lippolis, Vincenzo
collection PubMed
description An assessment of the natural ochratoxin A (OTA) exposure of seven Martina Franca jennies was carried out by analyzing blood and milk samples collected close to and after delivery. A total of 41 and 34 blood samples were collected from jennies and foals, respectively, and analyzed by ELISA. A total of 33 milk samples were collected from jennies and analyzed by the HPLC/FLD method based on IAC clean-up. Furthermore, 53 feed samples were collected from January to September and analyzed by a reference method (AOAC Official Method No. 2000.03) for OTA content. Feed samples showed OTA levels up to 2.7 ng/g with an incidence of 32%, while the OTA incidence rate in jennies’ blood samples was 73%, with a median value of 97 ng/L and concentrations ranging from <LOD to 6000 ng/L. A seasonal effect on OTA levels in positive blood samples was observed, with increases in the 53% of the positive ones from April to June. Concerning foals, the incidence rate of blood samples was 50%, with a median value of 52 ng/L, and concentrations ranged from <LOD to 4034 ng/L. The incidence of milk samples was 36%, with levels ranging from <LOD to 82 ng/L. In conclusion, the results showed a natural exposure of jennies and foals to OTA, and its presence in jenny milk could pose a risk for human newborns, considering its well-known nutritional and health properties.
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spelling pubmed-77598222020-12-26 Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery Lippolis, Vincenzo Asif, Shafaq Pascale, Michelangelo Cervellieri, Salvatore Mancini, Erminia Peli, Angelo De Amicis, Ippolito Robbe, Domenico Minervini, Fiorenza Toxins (Basel) Article An assessment of the natural ochratoxin A (OTA) exposure of seven Martina Franca jennies was carried out by analyzing blood and milk samples collected close to and after delivery. A total of 41 and 34 blood samples were collected from jennies and foals, respectively, and analyzed by ELISA. A total of 33 milk samples were collected from jennies and analyzed by the HPLC/FLD method based on IAC clean-up. Furthermore, 53 feed samples were collected from January to September and analyzed by a reference method (AOAC Official Method No. 2000.03) for OTA content. Feed samples showed OTA levels up to 2.7 ng/g with an incidence of 32%, while the OTA incidence rate in jennies’ blood samples was 73%, with a median value of 97 ng/L and concentrations ranging from <LOD to 6000 ng/L. A seasonal effect on OTA levels in positive blood samples was observed, with increases in the 53% of the positive ones from April to June. Concerning foals, the incidence rate of blood samples was 50%, with a median value of 52 ng/L, and concentrations ranged from <LOD to 4034 ng/L. The incidence of milk samples was 36%, with levels ranging from <LOD to 82 ng/L. In conclusion, the results showed a natural exposure of jennies and foals to OTA, and its presence in jenny milk could pose a risk for human newborns, considering its well-known nutritional and health properties. MDPI 2020-12-01 /pmc/articles/PMC7759822/ /pubmed/33271760 http://dx.doi.org/10.3390/toxins12120758 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Lippolis, Vincenzo
Asif, Shafaq
Pascale, Michelangelo
Cervellieri, Salvatore
Mancini, Erminia
Peli, Angelo
De Amicis, Ippolito
Robbe, Domenico
Minervini, Fiorenza
Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery
title Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery
title_full Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery
title_fullStr Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery
title_full_unstemmed Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery
title_short Natural Occurrence of Ochratoxin A in Blood and Milk Samples from Jennies and Their Foals after Delivery
title_sort natural occurrence of ochratoxin a in blood and milk samples from jennies and their foals after delivery
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759822/
https://www.ncbi.nlm.nih.gov/pubmed/33271760
http://dx.doi.org/10.3390/toxins12120758
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