The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance

Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial pathogen Bacillus anthracis. The bacterium presents a complex and dynamic composition of its cell envelope, which changes in response to developmental and environmental conditions and host-dependent signals. Becau...

Descripción completa

Detalles Bibliográficos
Autores principales: Chateau, Alice, Van der Verren, Sander E., Remaut, Han, Fioravanti, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759979/
https://www.ncbi.nlm.nih.gov/pubmed/33255913
http://dx.doi.org/10.3390/microorganisms8121864
_version_ 1783627224069439488
author Chateau, Alice
Van der Verren, Sander E.
Remaut, Han
Fioravanti, Antonella
author_facet Chateau, Alice
Van der Verren, Sander E.
Remaut, Han
Fioravanti, Antonella
author_sort Chateau, Alice
collection PubMed
description Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial pathogen Bacillus anthracis. The bacterium presents a complex and dynamic composition of its cell envelope, which changes in response to developmental and environmental conditions and host-dependent signals. Because of their easy to access extracellular locations, B. anthracis cell envelope components represent interesting targets for the identification and development of novel therapeutic and vaccine strategies. This review will focus on the novel insights regarding the composition, physiological role, and clinical relevance of B. anthracis cell envelope components.
format Online
Article
Text
id pubmed-7759979
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-77599792020-12-26 The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance Chateau, Alice Van der Verren, Sander E. Remaut, Han Fioravanti, Antonella Microorganisms Review Anthrax is a highly resilient and deadly disease caused by the spore-forming bacterial pathogen Bacillus anthracis. The bacterium presents a complex and dynamic composition of its cell envelope, which changes in response to developmental and environmental conditions and host-dependent signals. Because of their easy to access extracellular locations, B. anthracis cell envelope components represent interesting targets for the identification and development of novel therapeutic and vaccine strategies. This review will focus on the novel insights regarding the composition, physiological role, and clinical relevance of B. anthracis cell envelope components. MDPI 2020-11-26 /pmc/articles/PMC7759979/ /pubmed/33255913 http://dx.doi.org/10.3390/microorganisms8121864 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chateau, Alice
Van der Verren, Sander E.
Remaut, Han
Fioravanti, Antonella
The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance
title The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance
title_full The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance
title_fullStr The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance
title_full_unstemmed The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance
title_short The Bacillus anthracis Cell Envelope: Composition, Physiological Role, and Clinical Relevance
title_sort bacillus anthracis cell envelope: composition, physiological role, and clinical relevance
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759979/
https://www.ncbi.nlm.nih.gov/pubmed/33255913
http://dx.doi.org/10.3390/microorganisms8121864
work_keys_str_mv AT chateaualice thebacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance
AT vanderverrensandere thebacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance
AT remauthan thebacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance
AT fioravantiantonella thebacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance
AT chateaualice bacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance
AT vanderverrensandere bacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance
AT remauthan bacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance
AT fioravantiantonella bacillusanthraciscellenvelopecompositionphysiologicalroleandclinicalrelevance

Ejemplares similares