LNX1 Modulates Notch1 Signaling to Promote Expansion of the Glioma Stem Cell Population during Temozolomide Therapy in Glioblastoma

SIMPLE SUMMARY: Glioblastoma is the most common adult malignant brain tumor. It is an aggressive tumor that returns even after surgical removal and temozolomide-based chemotherapy and radiation. Our goal was to understand what genes are altered by temozolomide and how those genes may contribute to t...

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Detalles Bibliográficos
Autores principales: Baisiwala, Shivani, Hall, Robert R., Saathoff, Miranda R., M. Shireman, Jack, Park, Cheol, Budhiraja, Shreya, Goel, Chirag, Warnke, Louisa, Hardiman, Clare, Wang, Jennifer Y., McCortney, Katy, Horbinski, Craig M., Ahmed, Atique U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7759984/
https://www.ncbi.nlm.nih.gov/pubmed/33255632
http://dx.doi.org/10.3390/cancers12123505

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