Selective Chemical Functionalization at N6-Methyladenosine Residues in DNA Enabled by Visible-Light-Mediated Photoredox Catalysis

[Image: see text] Selective chemistry that modifies the structure of DNA and RNA is essential to understanding the role of epigenetic modifications. We report a visible-light-activated photocatalytic process that introduces a covalent modification at a C(sp(3))–H bond in the methyl group of N6-methy...

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Detalles Bibliográficos
Autores principales: Nappi, Manuel, Hofer, Alexandre, Balasubramanian, Shankar, Gaunt, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760100/
https://www.ncbi.nlm.nih.gov/pubmed/33305571
http://dx.doi.org/10.1021/jacs.0c10616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760100/
https://www.ncbi.nlm.nih.gov/pubmed/33305571
http://dx.doi.org/10.1021/jacs.0c10616

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