Use of Permanent Wall-Deficient Cells as a System for the Discovery of New-to-Nature Metabolites

Filamentous actinobacteria are widely used as microbial cell factories to produce valuable secondary metabolites, including the vast majority of clinically relevant antimicrobial compounds. Secondary metabolites are typically encoded by large biosynthetic gene clusters, which allow for a modular app...

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Detalles Bibliográficos
Autores principales: Shitut, Shraddha, Bergman, Güniz Özer, Kros, Alexander, Rozen, Daniel E., Claessen, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760116/
https://www.ncbi.nlm.nih.gov/pubmed/33265975
http://dx.doi.org/10.3390/microorganisms8121897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760116/
https://www.ncbi.nlm.nih.gov/pubmed/33265975
http://dx.doi.org/10.3390/microorganisms8121897

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