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Use of Permanent Wall-Deficient Cells as a System for the Discovery of New-to-Nature Metabolites
Filamentous actinobacteria are widely used as microbial cell factories to produce valuable secondary metabolites, including the vast majority of clinically relevant antimicrobial compounds. Secondary metabolites are typically encoded by large biosynthetic gene clusters, which allow for a modular app...
Autores principales: | Shitut, Shraddha, Bergman, Güniz Özer, Kros, Alexander, Rozen, Daniel E., Claessen, Dennis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760116/ https://www.ncbi.nlm.nih.gov/pubmed/33265975 http://dx.doi.org/10.3390/microorganisms8121897 |
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