A Comparison of p53 Isoform Profiles and Apoptosis Induced by Camptothecin or a Herbal Khat Extract (Catha Edulis (Vahl) Forssk. ex Endl.) in Leukemic Cell Lines: Exploring Cellular Responses in Therapy Development

SIMPLE SUMMARY: This study aimed at exploring the modulations of p53 in cell toxicity induced by an extract of the herb khat, a natural stimulant used by millions of people. We previously reported that khat-extract induced cell death by affecting mitochondrial function and the receptor- and mitochon...

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Detalles Bibliográficos
Autores principales: Onyango, Therese Bredholt, Hjelle, Sigrun M., Haaland, Ingvild, Vintermyr, Olav K., Johannessen, Anne Christine, Gjertsen, Bjørn Tore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760143/
https://www.ncbi.nlm.nih.gov/pubmed/33271840
http://dx.doi.org/10.3390/cancers12123596

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