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Amyloid β-Peptide Increases Mitochondria-Endoplasmic Reticulum Contact Altering Mitochondrial Function and Autophagosome Formation in Alzheimer’s Disease-Related Models

Recent findings have shown that the connectivity and crosstalk between mitochondria and the endoplasmic reticulum (ER) at mitochondria–ER contact sites (MERCS) are altered in Alzheimer’s disease (AD) and in AD-related models. MERCS have been related to the initial steps of autophagosome formation as...

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Detalles Bibliográficos
Autores principales: Leal, Nuno Santos, Dentoni, Giacomo, Schreiner, Bernadette, Naia, Luana, Piras, Antonio, Graff, Caroline, Cattaneo, Antonio, Meli, Giovanni, Hamasaki, Maho, Nilsson, Per, Ankarcrona, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760163/
https://www.ncbi.nlm.nih.gov/pubmed/33260715
http://dx.doi.org/10.3390/cells9122552