The 25 kDa H(CN) Domain of Clostridial Neurotoxins Is Indispensable for Their Neurotoxicity

The extraordinarily potent clostridial neurotoxins (CNTs) comprise tetanus neurotoxin (TeNT) and the seven established botulinum neurotoxin serotypes (BoNT/A-G). They are composed of four structurally independent domains: the roles of the catalytically active light chain, the translocation domain H(...

Descripción completa

Detalles Bibliográficos
Autores principales: Deppe, Julian, Weisemann, Jasmin, Mahrhold, Stefan, Rummel, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760224/
https://www.ncbi.nlm.nih.gov/pubmed/33255952
http://dx.doi.org/10.3390/toxins12120743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760224/
https://www.ncbi.nlm.nih.gov/pubmed/33255952
http://dx.doi.org/10.3390/toxins12120743

Ejemplares similares