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HSV-1 Oncolytic Viruses from Bench to Bedside: An Overview of Current Clinical Trials

SIMPLE SUMMARY: Oncolytic Herpes simplex virus-1 (HSV-1) offers the dual potential of both lytic tumor-specific cell killing and inducing anti-tumor immune responses. The HSV-1 genome can be altered to enhance both components and this may be applicable for the treatment of a broad range of cancers....

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Detalles Bibliográficos
Autores principales:	Koch, Marilin S., Lawler, Sean E., Chiocca, E. Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760226/ https://www.ncbi.nlm.nih.gov/pubmed/33255871 http://dx.doi.org/10.3390/cancers12123514

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