Cargando…

Extracellular Vesicle-Based Therapeutics: Preclinical and Clinical Investigations

Drug nanoformulations hold remarkable promise for the efficient delivery of therapeutics to a disease site. Unfortunately, artificial nanocarriers, mostly liposomes and polymeric nanoparticles, show limited applications due to the unfavorable pharmacokinetics and rapid clearance from the blood circu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klyachko, Natalia L., Arzt, Camryn J., Li, Samuel M., Gololobova, Olesia A., Batrakova, Elena V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760239/ https://www.ncbi.nlm.nih.gov/pubmed/33271883 http://dx.doi.org/10.3390/pharmaceutics12121171

Ejemplares similares

Using Extracellular Vesicles Released by GDNF-Transfected Macrophages for Therapy of Parkinson Disease
por: Zhao, Yuling, et al.
Publicado: (2022)

Longitudinal characterization of circulating extracellular vesicles and small RNA during simian immunodeficiency virus infection and antiretroviral therapy
por: Huang, Yiyao, et al.
Publicado: (2023)

Label‐free characterization of an extracellular vesicle‐based therapeutic
por: Priglinger, Eleni, et al.
Publicado: (2021)

Extracellular Vesicles as Drug Carriers for Enzyme Replacement Therapy to Treat CLN2 Batten Disease: Optimization of Drug Administration Routes
por: Haney, Matthew J., et al.
Publicado: (2020)

An ex vivo model of interactions between extracellular vesicles and peripheral mononuclear blood cells in whole blood
por: Rodriguez, Blanca V., et al.
Publicado: (2023)

miR-210 Expression Is Strongly Hypoxia-Induced in Anaplastic Thyroid Cancer Cell Lines and Is Associated with Extracellular Vesicles and Argonaute-2
por: Powell, Bonita H., et al.
Publicado: (2023)

Focus on Extracellular Vesicles: Development of Extracellular Vesicle-Based Therapeutic Systems
por: Ohno, Shin-ichiro, et al.
Publicado: (2016)

Therapeutic potential of stem cell-derived extracellular vesicles in osteoarthritis: preclinical study findings
por: Kim, Ki Hoon, et al.
Publicado: (2020)

Characteristics of Extracellular Vesicles and Preclinical Testing Considerations Prior to Clinical Applications
por: Yoo, Min Heui, et al.
Publicado: (2022)

Extracellular vesicles enhance pulmonary transduction of stably associated adeno‐associated virus following intratracheal administration
por: Kwak, Gijung, et al.
Publicado: (2023)

Therapeutic potential of extracellular vesicles in preclinical stroke models: a systematic review and meta-analysis
por: Thomas, Josephine M, et al.
Publicado: (2020)

Leptin-loaded Extracellular Vesicles Treat Sleep-disordered Breathing in Mice with Obesity
por: Freire, Carla, et al.
Publicado: (2022)

Manufacturing of Human Extracellular Vesicle-Based Therapeutics for Clinical Use
por: Gimona, Mario, et al.
Publicado: (2017)

Extracellular Vesicles as Therapeutic Resources in the Clinical Environment
por: Sanz-Ros, Jorge, et al.
Publicado: (2023)

Characterization of extracellular vesicles and synthetic nanoparticles with four orthogonal single‐particle analysis platforms
por: Arab, Tanina, et al.
Publicado: (2021)

Specific Transfection of Inflamed Brain by Macrophages: A New Therapeutic Strategy for Neurodegenerative Diseases
por: Haney, Matthew J., et al.
Publicado: (2013)

Extracellular Vesicle-Based Therapeutics for Heart Repair
por: Saludas, Laura, et al.
Publicado: (2021)

Extracellular Vesicle-Based Therapeutics in Neurological Disorders
por: Yuan, Yiwen, et al.
Publicado: (2022)

Insights on Localized and Systemic Delivery of Redox-Based Therapeutics
por: Buglak, Nicholas E., et al.
Publicado: (2018)

Therapeutic Potential of Extracellular Vesicles
por: Merino, Ana Maria, et al.
Publicado: (2014)

Therapeutic potential of stem cell extracellular vesicles for ischemic stroke in preclinical rodent models: a meta-analysis
por: Zhao, Jing, et al.
Publicado: (2023)

Therapeutic Prospects of Extracellular Vesicles in Cancer Treatment
por: Chulpanova, Daria S., et al.
Publicado: (2018)

Focus on Extracellular Vesicles: Therapeutic Potential of Stem Cell-Derived Extracellular Vesicles
por: Zhang, Bin, et al.
Publicado: (2016)

Extracellular Vesicles Released by Genetically Modified Macrophages Activate Autophagy and Produce Potent Neuroprotection in Mouse Model of Lysosomal Storage Disorder, Batten Disease
por: El-Hage, Nazira, et al.
Publicado: (2023)

Advances of engineered extracellular vesicles-based therapeutics strategy
por: Komuro, Hiroaki, et al.
Publicado: (2022)

Extracellular-Vesicle-Based Therapeutics in Neuro-Ophthalmic Disorders
por: Massoumi, Hamed, et al.
Publicado: (2023)

Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper
por: Lener, Thomas, et al.
Publicado: (2015)

Reprogramming Extracellular Vesicles for Protein Therapeutics Delivery
por: Ovchinnikova, Leyla A., et al.
Publicado: (2021)

Extracellular Vesicles, Ageing, and Therapeutic Interventions
por: Panagiotou, Nikolaos, et al.
Publicado: (2018)

On the Choice of the Extracellular Vesicles for Therapeutic Purposes
por: Campanella, Claudia, et al.
Publicado: (2019)

Extracellular Vesicles in the Development of Cancer Therapeutics
por: Sun, Haoyao, et al.
Publicado: (2020)

Therapeutic Potential of Engineered Extracellular Vesicles
por: Mentkowski, Kyle I., et al.
Publicado: (2018)

Diagnostic and Therapeutic Potential of Extracellular Vesicles
por: Kodam, Sai Priyanka, et al.
Publicado: (2021)

Extracellular Vesicles—Oral Therapeutics of the Future
por: Cieślik, Martyna, et al.
Publicado: (2022)

Advances in Therapeutic Applications of Extracellular Vesicles
por: Zhang, Yiming, et al.
Publicado: (2023)

Stem cells and extracellular vesicles to improve preclinical orofacial soft tissue healing
por: Wang, Zhihao, et al.
Publicado: (2023)

Preclinical efficacy and clinical safety of clinical‐grade nebulized allogenic adipose mesenchymal stromal cells‐derived extracellular vesicles
por: Shi, Meng‐meng, et al.
Publicado: (2021)

Extracellular Vesicles as Therapeutic Tools for the Treatment of Chronic Wounds
por: Bray, Eric R., et al.
Publicado: (2021)

Preservation techniques of stem cells extracellular vesicles: a gate for manufacturing of clinical grade therapeutic extracellular vesicles and long-term clinical trials
por: Bahr, Mohamed M., et al.
Publicado: (2020)

Functional assays to assess the therapeutic potential of extracellular vesicles
por: Nguyen, Vivian V.T., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7ci2l5buibv1ps77liljegm3ls