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Metabolomic Analysis of Plasma from GABA(B(1)) Knock-Out Mice Reveals Decreased Levels of Elaidic Trans-Fatty Acid

Mice lacking the GABA(B(1)) subunit of gamma-aminobutyric acid (GABA) type B receptors exhibit spontaneous seizures, hyperalgesia, hyperlocomotor activity, and memory impairment. Although mice lacking the GABA(B(1)) subunit are viable, they are sterile, and to generate knockout (KO) mice, it is nece...

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Detalles Bibliográficos
Autores principales: Fattuoni, Claudia, Barberini, Luigi, Noto, Antonio, Follesa, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760308/
https://www.ncbi.nlm.nih.gov/pubmed/33255896
http://dx.doi.org/10.3390/metabo10120484