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Bile Acids and GPBAR-1: Dynamic Interaction Involving Genes, Environment and Gut Microbiome
Bile acids (BA) are amphiphilic molecules synthesized in the liver from cholesterol. BA undergo continuous enterohepatic recycling through intestinal biotransformation by gut microbiome and reabsorption into the portal tract for uptake by hepatocytes. BA are detergent molecules aiding the digestion...
Autores principales: | Portincasa, Piero, Di Ciaula, Agostino, Garruti, Gabriella, Vacca, Mirco, De Angelis, Maria, Wang, David Q.-H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760347/ https://www.ncbi.nlm.nih.gov/pubmed/33266235 http://dx.doi.org/10.3390/nu12123709 |
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