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Novel Antioxidant Therapy with the Immediate Precursor to Glutathione, γ-Glutamylcysteine (GGC), Ameliorates LPS-Induced Cellular Stress in In Vitro 3D-Differentiated Airway Model from Primary Cystic Fibrosis Human Bronchial Cells

Systemic glutathione deficiency, inflammation, and oxidative stress are hallmarks of cystic fibrosis (CF), an inherited disease that causes persistent lung infections and severe damage to the respiratory system and many of the body organs. Improvements to current antioxidant therapeutic strategies a...

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Detalles Bibliográficos
Autores principales: Hewson, Chris K., Capraro, Alexander, Wong, Sharon L., Pandzic, Elvis, Zhong, Ling, Fernando, Bentotage S. M., Awatade, Nikhil T., Hart-Smith, Gene, Whan, Renee M., Thomas, Shane R., Jaffe, Adam, Bridge, Wallace J., Waters, Shafagh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760366/
https://www.ncbi.nlm.nih.gov/pubmed/33266084
http://dx.doi.org/10.3390/antiox9121204

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