Extreme venous letting and cupping resulting in life-threatening anemia and acute myocardial infarction: A case report

BACKGROUND: Wet cupping (WC) is a traditional therapy of skin suction-assisted bloodletting that is widely used in modern alternative medicine in Asia and the Middle East. Herein, we report the case of a male who presented with ST-elevation myocardial infarction (STEMI) and life-threatening anemia and underwent excessive WC. CASE SUMMARY: A 55-year-old male presented with chest pain (30 min) and dyspnea (3 wk). His initial electrocardiogram suggested STEMI in the anterior wall. Furthermore, his laboratory results showed severe anemia with a hemoglobin level of 4.1 g/dL. Of note, the patient underwent regular WC therapy for chronic back pain, which he had recently intensified. His WC practice resulted in life-threatening anemia and eventually STEMI. Percutaneous coronary intervention in the left anterior descending artery was performed to treat the STEMI. His dyspnea dramatically improved after the transfusion, and his hemoglobin level returned to 14.8 g/dL within 2 mo after discharge. He has been uneventful for the last seven years of follow-up. CONCLUSION: The current case demonstrates that excessive WC without adequate medical monitoring can result in severe anemia, which can further develop into STEMI.