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Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF)

The increasing number of infections caused by multidrug-resistant bacteria requires an intensified search for new antibiotics. Pep19-4LF is a synthetic antimicrobial peptide (GKKYRRFRWKFKGKLFLFG) that was previously designed with the main focus on high antimicrobial activity. The hydrophobic motif,...

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Detalles Bibliográficos
Autores principales: Storck, Philip, Umstätter, Florian, Wohlfart, Sabrina, Domhan, Cornelius, Kleist, Christian, Werner, Julia, Brandenburg, Klaus, Zimmermann, Stefan, Haberkorn, Uwe, Mier, Walter, Uhl, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760514/
https://www.ncbi.nlm.nih.gov/pubmed/33255900
http://dx.doi.org/10.3390/antibiotics9120844