Cargando…
Fatty Acid Conjugation Leads to Length-Dependent Antimicrobial Activity of a Synthetic Antibacterial Peptide (Pep19-4LF)
The increasing number of infections caused by multidrug-resistant bacteria requires an intensified search for new antibiotics. Pep19-4LF is a synthetic antimicrobial peptide (GKKYRRFRWKFKGKLFLFG) that was previously designed with the main focus on high antimicrobial activity. The hydrophobic motif,...
Autores principales: | Storck, Philip, Umstätter, Florian, Wohlfart, Sabrina, Domhan, Cornelius, Kleist, Christian, Werner, Julia, Brandenburg, Klaus, Zimmermann, Stefan, Haberkorn, Uwe, Mier, Walter, Uhl, Philipp |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760514/ https://www.ncbi.nlm.nih.gov/pubmed/33255900 http://dx.doi.org/10.3390/antibiotics9120844 |
Ejemplares similares
-
Vancomycin Resistance Is Overcome by Conjugation of Polycationic Peptides
por: Umstätter, Florian, et al.
Publicado: (2020) -
Vancomycin-Lipopeptide Conjugates with High Antimicrobial Activity on Vancomycin-Resistant Enterococci
por: Mühlberg, Eric, et al.
Publicado: (2020) -
Impact of Linker Modification and PEGylation of Vancomycin Conjugates on Structure-Activity Relationships and Pharmacokinetics
por: Umstätter, Florian, et al.
Publicado: (2022) -
Replacement of l-Amino Acids by d-Amino Acids in the Antimicrobial Peptide Ranalexin and Its Consequences for Antimicrobial Activity and Biodistribution
por: Domhan, Cornelius, et al.
Publicado: (2019) -
Mass Spectrometric Quantification of the Antimicrobial Peptide Pep19-2.5 with Stable Isotope Labeling and Acidic Hydrolysis
por: Wohlfart, Sabrina, et al.
Publicado: (2021)