Polarized Cytokine Release Triggered by P2X7 Receptor from Retinal Pigmented Epithelial Cells Dependent on Calcium Influx

Cytokine release from non-inflammatory cells is a key step in innate immunity, and agonists triggering cytokine release are central in coordinating responses. P2X7 receptor (P2X7R) stimulation by extracellular ATP is best known to active the NLRP3 inflammasome and release IL-1β, but stimulation also...

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Detalles Bibliográficos
Autores principales: Shao, Xiaolei, Guha, Sonia, Lu, Wennan, Campagno, Keith E., Beckel, Jonathan M., Mills, Jason A., Yang, Wenli, Mitchell, Claire H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760537/
https://www.ncbi.nlm.nih.gov/pubmed/33255431
http://dx.doi.org/10.3390/cells9122537

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