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Melatonin/Nrf2/NLRP3 Connection in Mouse Heart Mitochondria during Aging

Aging is a major risk for cardiovascular diseases (CVD). Age-related disorders include oxidative stress, mitochondria dysfunction, and exacerbation of the NF-κB/NLRP3 innate immune response pathways. Some of the molecular mechanisms underlying these processes, however, remain unclear. This study tes...

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Detalles Bibliográficos
Autores principales: Fernández-Ortiz, Marisol, Sayed, Ramy K. A., Fernández-Martínez, José, Cionfrini, Antonia, Aranda-Martínez, Paula, Escames, Germaine, de Haro, Tomás, Acuña-Castroviejo, Darío
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760557/
https://www.ncbi.nlm.nih.gov/pubmed/33260800
http://dx.doi.org/10.3390/antiox9121187