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Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium

SIMPLE SUMMARY: Semen collection in donkey jacks can last up to 90 min due to the long courtship needed for this species’ males to obtain sexual excitation and erection. In several domestic animals, ProstaglandinF2α successfully stimulated excitement in the male prior to collection and enhanced seme...

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Autores principales: Panzani, Duccio, Quaresma, Miguel, Fanelli, Diana, Camillo, Francesco, Moroni, Rebecca, Rota, Alessandra, Martins-Bessa, Ana, Nóvoa, Miguel, Catalán, Jaime, Canisso, Igor F., Conte, Giuseppe, Mirò, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760598/
https://www.ncbi.nlm.nih.gov/pubmed/33261078
http://dx.doi.org/10.3390/ani10122231
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author Panzani, Duccio
Quaresma, Miguel
Fanelli, Diana
Camillo, Francesco
Moroni, Rebecca
Rota, Alessandra
Martins-Bessa, Ana
Nóvoa, Miguel
Catalán, Jaime
Canisso, Igor F.
Conte, Giuseppe
Mirò, Jordi
author_facet Panzani, Duccio
Quaresma, Miguel
Fanelli, Diana
Camillo, Francesco
Moroni, Rebecca
Rota, Alessandra
Martins-Bessa, Ana
Nóvoa, Miguel
Catalán, Jaime
Canisso, Igor F.
Conte, Giuseppe
Mirò, Jordi
author_sort Panzani, Duccio
collection PubMed
description SIMPLE SUMMARY: Semen collection in donkey jacks can last up to 90 min due to the long courtship needed for this species’ males to obtain sexual excitation and erection. In several domestic animals, ProstaglandinF2α successfully stimulated excitement in the male prior to collection and enhanced semen production. In our study, the prostaglandin analog cloprostenol sodium, administered prior to the semen collection, hastened erection and ejaculation in almost all donkey jacks. No differences have been found in semen production compared to control. ABSTRACT: Due to the long courtship needed to attain excitation and erection, donkey semen collection can take up to 90 min. ProstaglandinF2α (PGF2α) has been reported to hasten the onset of erection and ejaculation in domesticated mammals, presumably by inducing smooth muscle contractions in the internal genitalia. However, while it has been anecdotally used in donkeys, it has yet to be critically evaluated. This study aimed to compare behavioral and semen parameters in Catalan, Balearic, Amiata, and Miranda jacks treated with the PGF2α analogue cloprostenol sodium immediately prior to exposure to an estrus jenny. Nineteen donkeys were assigned in a crossover design to receive cloprostenol sodium (125 µg, i.m.; n = 53 collections) or saline (1 mL, i.m.; n = 53 collections). There were no differences for erection (52/53 vs. 52/53) or ejaculation (52/53 vs. 48/53) for collection attempts assigned to saline or cloprostenol sodium, respectively. Cloprostenol sodium significantly hastened treatment-to-erection and treatment-to-ejaculation times from 12.0 ± 1.6 to 6.0 ± 1.6 min and from 14.0 ± 1.4 to 9.6 ± 1.4 min, respectively. Significant effects of breed and age were observed in behavioral and parameters, but there were no effects of cloprostenol sodium administration on semen parameters. In conclusion, cloprostenol sodium administration immediately prior to semen collection hastened time to collect semen in donkeys with no detrimental effects on semen quality and can be used by practitioners to circumvent long delays in donkey semen collection.
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spelling pubmed-77605982020-12-26 Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium Panzani, Duccio Quaresma, Miguel Fanelli, Diana Camillo, Francesco Moroni, Rebecca Rota, Alessandra Martins-Bessa, Ana Nóvoa, Miguel Catalán, Jaime Canisso, Igor F. Conte, Giuseppe Mirò, Jordi Animals (Basel) Article SIMPLE SUMMARY: Semen collection in donkey jacks can last up to 90 min due to the long courtship needed for this species’ males to obtain sexual excitation and erection. In several domestic animals, ProstaglandinF2α successfully stimulated excitement in the male prior to collection and enhanced semen production. In our study, the prostaglandin analog cloprostenol sodium, administered prior to the semen collection, hastened erection and ejaculation in almost all donkey jacks. No differences have been found in semen production compared to control. ABSTRACT: Due to the long courtship needed to attain excitation and erection, donkey semen collection can take up to 90 min. ProstaglandinF2α (PGF2α) has been reported to hasten the onset of erection and ejaculation in domesticated mammals, presumably by inducing smooth muscle contractions in the internal genitalia. However, while it has been anecdotally used in donkeys, it has yet to be critically evaluated. This study aimed to compare behavioral and semen parameters in Catalan, Balearic, Amiata, and Miranda jacks treated with the PGF2α analogue cloprostenol sodium immediately prior to exposure to an estrus jenny. Nineteen donkeys were assigned in a crossover design to receive cloprostenol sodium (125 µg, i.m.; n = 53 collections) or saline (1 mL, i.m.; n = 53 collections). There were no differences for erection (52/53 vs. 52/53) or ejaculation (52/53 vs. 48/53) for collection attempts assigned to saline or cloprostenol sodium, respectively. Cloprostenol sodium significantly hastened treatment-to-erection and treatment-to-ejaculation times from 12.0 ± 1.6 to 6.0 ± 1.6 min and from 14.0 ± 1.4 to 9.6 ± 1.4 min, respectively. Significant effects of breed and age were observed in behavioral and parameters, but there were no effects of cloprostenol sodium administration on semen parameters. In conclusion, cloprostenol sodium administration immediately prior to semen collection hastened time to collect semen in donkeys with no detrimental effects on semen quality and can be used by practitioners to circumvent long delays in donkey semen collection. MDPI 2020-11-27 /pmc/articles/PMC7760598/ /pubmed/33261078 http://dx.doi.org/10.3390/ani10122231 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Panzani, Duccio
Quaresma, Miguel
Fanelli, Diana
Camillo, Francesco
Moroni, Rebecca
Rota, Alessandra
Martins-Bessa, Ana
Nóvoa, Miguel
Catalán, Jaime
Canisso, Igor F.
Conte, Giuseppe
Mirò, Jordi
Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium
title Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium
title_full Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium
title_fullStr Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium
title_full_unstemmed Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium
title_short Hastening Time to Ejaculation in Donkey Jacks Treated with the PGF2α Analog, Cloprostenol Sodium
title_sort hastening time to ejaculation in donkey jacks treated with the pgf2α analog, cloprostenol sodium
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760598/
https://www.ncbi.nlm.nih.gov/pubmed/33261078
http://dx.doi.org/10.3390/ani10122231
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