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Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders
Background: We evaluated the prevalence of psychiatric disorders in mild traumatic brain injury (MTBI) patients and investigated psychiatric comorbidity in relation to subjective symptoms and return to work (RTW). Methods: We recruited 103 MTBI patients (mean age 40.8 years, SD 3.1) prospectively fr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760617/ https://www.ncbi.nlm.nih.gov/pubmed/33260933 http://dx.doi.org/10.3390/brainsci10120916 |
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author | Marinkovic, Ivan Isokuortti, Harri Huovinen, Antti Trpeska Marinkovic, Daniela Mäki, Kaisa Nybo, Taina Korvenoja, Antti Rahul, Raj Vataja, Risto Melkas, Susanna |
author_facet | Marinkovic, Ivan Isokuortti, Harri Huovinen, Antti Trpeska Marinkovic, Daniela Mäki, Kaisa Nybo, Taina Korvenoja, Antti Rahul, Raj Vataja, Risto Melkas, Susanna |
author_sort | Marinkovic, Ivan |
collection | PubMed |
description | Background: We evaluated the prevalence of psychiatric disorders in mild traumatic brain injury (MTBI) patients and investigated psychiatric comorbidity in relation to subjective symptoms and return to work (RTW). Methods: We recruited 103 MTBI patients (mean age 40.8 years, SD 3.1) prospectively from University Hospital. The patients were followed up for one year. The Rivermead Post-Concussion Symptom Questionnaire (RPQ) and Extended Glasgow Outcome Scale (GOSE) were administered one month after MTBI. Three months after MTBI, any psychiatric disorders were assessed using the Structured Clinical Interview for DSM-IV Axis I Disorders. Results: Psychiatric disorders were diagnosed in 26 patients (25.2%). The most common disorders were previous/current depression. At three months, there was no difference between patients with psychiatric disorders versus those without them in RTW (95.7% vs. 87.3%, p = 0.260) or at least in part-time work (100% vs. 94.4%, p = 0.245). In Kaplan–Meier analysis, the median time to RTW was 10 days for both groups. The median RPQ score was 13.0 (Interquartile range (IQR) 6.5–19.0) in patients with a psychiatric disorder compared to 8.5 (IQR 2.3–14.0) in those without one (p = 0.021); respectively, the median GOSE was 7.0 (IQR 7.0–8.0) compared to 8.0 (IQR 7.0–8.0, p = 0.003). Conclusions: Approximately every fourth patient with MTBI had a psychiatric disorder. These patients reported more symptoms, and their functional outcome measured with GOSE at one month after MTBI was worse. However, presence of any psychiatric disorder did not affect RTW. Early contact and adequate follow-up are important when supporting the patient’s return to work. |
format | Online Article Text |
id | pubmed-7760617 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-77606172020-12-26 Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders Marinkovic, Ivan Isokuortti, Harri Huovinen, Antti Trpeska Marinkovic, Daniela Mäki, Kaisa Nybo, Taina Korvenoja, Antti Rahul, Raj Vataja, Risto Melkas, Susanna Brain Sci Article Background: We evaluated the prevalence of psychiatric disorders in mild traumatic brain injury (MTBI) patients and investigated psychiatric comorbidity in relation to subjective symptoms and return to work (RTW). Methods: We recruited 103 MTBI patients (mean age 40.8 years, SD 3.1) prospectively from University Hospital. The patients were followed up for one year. The Rivermead Post-Concussion Symptom Questionnaire (RPQ) and Extended Glasgow Outcome Scale (GOSE) were administered one month after MTBI. Three months after MTBI, any psychiatric disorders were assessed using the Structured Clinical Interview for DSM-IV Axis I Disorders. Results: Psychiatric disorders were diagnosed in 26 patients (25.2%). The most common disorders were previous/current depression. At three months, there was no difference between patients with psychiatric disorders versus those without them in RTW (95.7% vs. 87.3%, p = 0.260) or at least in part-time work (100% vs. 94.4%, p = 0.245). In Kaplan–Meier analysis, the median time to RTW was 10 days for both groups. The median RPQ score was 13.0 (Interquartile range (IQR) 6.5–19.0) in patients with a psychiatric disorder compared to 8.5 (IQR 2.3–14.0) in those without one (p = 0.021); respectively, the median GOSE was 7.0 (IQR 7.0–8.0) compared to 8.0 (IQR 7.0–8.0, p = 0.003). Conclusions: Approximately every fourth patient with MTBI had a psychiatric disorder. These patients reported more symptoms, and their functional outcome measured with GOSE at one month after MTBI was worse. However, presence of any psychiatric disorder did not affect RTW. Early contact and adequate follow-up are important when supporting the patient’s return to work. MDPI 2020-11-27 /pmc/articles/PMC7760617/ /pubmed/33260933 http://dx.doi.org/10.3390/brainsci10120916 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Marinkovic, Ivan Isokuortti, Harri Huovinen, Antti Trpeska Marinkovic, Daniela Mäki, Kaisa Nybo, Taina Korvenoja, Antti Rahul, Raj Vataja, Risto Melkas, Susanna Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders |
title | Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders |
title_full | Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders |
title_fullStr | Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders |
title_full_unstemmed | Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders |
title_short | Prognosis after Mild Traumatic Brain Injury: Influence of Psychiatric Disorders |
title_sort | prognosis after mild traumatic brain injury: influence of psychiatric disorders |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760617/ https://www.ncbi.nlm.nih.gov/pubmed/33260933 http://dx.doi.org/10.3390/brainsci10120916 |
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