Fluorescent Tagged Vaccinia Virus Genome Allows Rapid and Efficient Measurement of Oncolytic Potential and Discovery of Oncolytic Modulators

As a live biologic agent, oncolytic vaccinia virus has the ability to target and selectively amplify at tumor sites. We have previously reported that deletion of thymidine kinase and ribonucleotide reductase genes in vaccinia virus can increase the safety and efficacy of the virus. Here, to allow di...

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Detalles Bibliográficos
Autores principales: Gallardo, Franck, Schmitt, Doris, Brandely, Renée, Brua, Catherine, Silvestre, Nathalie, Findeli, Annie, Foloppe, Johann, Top, Sokunthea, Kappler-Gratias, Sandrine, Quentin-Froignant, Charlotte, Morin, Renaud, Lagarde, Jean-Michel, Bystricky, Kerstin, Bertagnoli, Stéphane, Erbs, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760631/
https://www.ncbi.nlm.nih.gov/pubmed/33256205
http://dx.doi.org/10.3390/biomedicines8120543

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