ASC-Mediated Inflammation and Pyroptosis Attenuates Brucella abortus Pathogenesis Following the Recognition of gDNA

Brucella abortus is a zoonotic pathogen that causes brucellosis. Because of Brucella’s unique LPS layer and intracellular localization predominately within macrophages, it can often evade immune detection. However, pattern recognition receptors are capable of sensing Brucella pathogen-associated mol...

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Detalles Bibliográficos
Autores principales: Tupik, Juselyn D., Coutermarsh-Ott, Sheryl L., Benton, Angela H., King, Kellie A., Kiryluk, Hanna D., Caswell, Clayton C., Allen, Irving C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760712/
https://www.ncbi.nlm.nih.gov/pubmed/33266295
http://dx.doi.org/10.3390/pathogens9121008

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