The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin

Respiratory syncytial virus (RSV) is associated with adverse outcomes among immunocompromised patients. Inhaled ribavirin has been shown to improve mortality rates. The Small-Particle Aerosol Generator delivery system (SPAG-2) is the only FDA-cleared device to deliver inhaled ribavirin. However, it...

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Detalles Bibliográficos
Autores principales: Dallas, Ronald H., Rains, Jason K., Wilder, Keith, Humphrey, William, Cross, Shane J., Ghafoor, Saad, Brazelton de Cardenas, Jessica N., Hayden, Randall T., Hijano, Diego R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760766/
https://www.ncbi.nlm.nih.gov/pubmed/33260359
http://dx.doi.org/10.3390/pharmaceutics12121163
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author Dallas, Ronald H.
Rains, Jason K.
Wilder, Keith
Humphrey, William
Cross, Shane J.
Ghafoor, Saad
Brazelton de Cardenas, Jessica N.
Hayden, Randall T.
Hijano, Diego R.
author_facet Dallas, Ronald H.
Rains, Jason K.
Wilder, Keith
Humphrey, William
Cross, Shane J.
Ghafoor, Saad
Brazelton de Cardenas, Jessica N.
Hayden, Randall T.
Hijano, Diego R.
author_sort Dallas, Ronald H.
collection PubMed
description Respiratory syncytial virus (RSV) is associated with adverse outcomes among immunocompromised patients. Inhaled ribavirin has been shown to improve mortality rates. The Small-Particle Aerosol Generator delivery system (SPAG-2) is the only FDA-cleared device to deliver inhaled ribavirin. However, it is difficult to set up and maintain. We developed a method for delivery of this medication using the vibrating mesh nebulizer (Aerogen(®)). We did not observe any adverse events with this method.
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spelling pubmed-77607662020-12-26 The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin Dallas, Ronald H. Rains, Jason K. Wilder, Keith Humphrey, William Cross, Shane J. Ghafoor, Saad Brazelton de Cardenas, Jessica N. Hayden, Randall T. Hijano, Diego R. Pharmaceutics Communication Respiratory syncytial virus (RSV) is associated with adverse outcomes among immunocompromised patients. Inhaled ribavirin has been shown to improve mortality rates. The Small-Particle Aerosol Generator delivery system (SPAG-2) is the only FDA-cleared device to deliver inhaled ribavirin. However, it is difficult to set up and maintain. We developed a method for delivery of this medication using the vibrating mesh nebulizer (Aerogen(®)). We did not observe any adverse events with this method. MDPI 2020-11-29 /pmc/articles/PMC7760766/ /pubmed/33260359 http://dx.doi.org/10.3390/pharmaceutics12121163 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Communication
Dallas, Ronald H.
Rains, Jason K.
Wilder, Keith
Humphrey, William
Cross, Shane J.
Ghafoor, Saad
Brazelton de Cardenas, Jessica N.
Hayden, Randall T.
Hijano, Diego R.
The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin
title The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin
title_full The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin
title_fullStr The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin
title_full_unstemmed The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin
title_short The Aerogen(®) Solo Is an Alternative to the Small Particle Aerosol Generator (SPAG-2) for Administration of Inhaled Ribavirin
title_sort aerogen(®) solo is an alternative to the small particle aerosol generator (spag-2) for administration of inhaled ribavirin
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760766/
https://www.ncbi.nlm.nih.gov/pubmed/33260359
http://dx.doi.org/10.3390/pharmaceutics12121163
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