Cargando…

Comprehensive Transcriptomic Analysis Identifies ST8SIA1 as a Survival-Related Sialyltransferase Gene in Breast Cancer

Hypersialylation caused by the overexpression of sialyltransferases (STs) is a common feature in cancer that is associated with several characteristics of tumorigenesis. Thus, identifying cancer-associated STs is critical for cancer therapy. However, ST screening has been frequently conducted in cel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kan, Jung-Yu, Moi, Sin-Hua, Hung, Wen-Chun, Hou, Ming-Feng, Chen, Fang-Ming, Shih, Shen-Liang, Shiau, Jun-Ping, Li, Chung-Liang, Chiang, Chih-Po
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760851/ https://www.ncbi.nlm.nih.gov/pubmed/33260650 http://dx.doi.org/10.3390/genes11121436

Ejemplares similares

Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective
por: Venuto, Marzia Tindara, et al.
Publicado: (2020)

Evolutionary history of the alpha2,8-sialyltransferase (ST8Sia) gene family: Tandem duplications in early deuterostomes explain most of the diversity found in the vertebrate ST8Sia genes
por: Harduin-Lepers, Anne, et al.
Publicado: (2008)

Novel Zebrafish Mono-α2,8-sialyltransferase (ST8Sia VIII): An Evolutionary Perspective of α2,8-Sialylation
por: Chang, Lan-Yi, et al.
Publicado: (2019)

Upregulation of Human ST8Sia VI (α2,8-Sialyltransferase) Gene Expression by Physcion in SK-N-BE(2)-C Human Neuroblastoma Cells
por: Yoon, Hyun-Kyoung, et al.
Publicado: (2016)

Intrabodies against the Polysialyltransferases ST8SiaII and ST8SiaIV inhibit Polysialylation of NCAM in rhabdomyosarcoma tumor cells
por: Somplatzki, Stefan, et al.
Publicado: (2017)

Knockout of the polysialyltransferases ST8SiaII and ST8SiaIV leads to a dilatation of rete testis during postnatal development
por: Humpfle, Luisa, et al.
Publicado: (2023)

Sensory Experience Differentially Modulates the mRNA Expression of the Polysialyltransferases ST8SiaII and ST8SiaIV in Postnatal Mouse Visual Cortex
por: Bélanger, Marie-Claude, et al.
Publicado: (2011)

Comprehensive Transcriptomic and Proteomic Analyses Identify a Candidate Gene Set in Cross-Resistance for Endocrine Therapy in Breast Cancer
por: Li, Chung-Liang, et al.
Publicado: (2022)

Bioinformatics Analyses Identify the Therapeutic Potential of ST8SIA6 for Colon Cancer
por: Ko, Chou-Yuan, et al.
Publicado: (2022)

Role of GD3 Synthase ST8Sia I in Cancers
por: Kasprowicz, Angelina, et al.
Publicado: (2022)

Variants of ST8SIA1 Are Associated with Risk of Developing Multiple Sclerosis
por: Husain, Seema, et al.
Publicado: (2008)

ST8SIA2 promotes oligodendrocyte differentiation and the integrity of myelin and axons
por: Szewczyk, Lukasz Mateusz, et al.
Publicado: (2016)

Pharmacological Inhibition of polysialyltransferase ST8SiaII Modulates Tumour Cell Migration
por: Al-Saraireh, Yousef M. J., et al.
Publicado: (2013)

Estradiol Represses the G(D3) Synthase Gene ST8SIA1 Expression in Human Breast Cancer Cells by Preventing NFκB Binding to ST8SIA1 Promoter
por: Bobowski, Marie, et al.
Publicado: (2013)

Comprehensive profiles and diagnostic value of menopausal-specific gut microbiota in premenopausal breast cancer
por: Hou, Ming-Feng, et al.
Publicado: (2021)

Regulation of inflammatory signaling by the ST6Gal-I sialyltransferase
por: Holdbrooks, Andrew T., et al.
Publicado: (2020)

Positive selection on schizophrenia-associated ST8SIA2 gene in post-glacial Asia
por: Fujito, Naoko T., et al.
Publicado: (2018)

Effect of expression alteration in flanking genes on phenotypes of St8sia2-deficient mice
por: Ikegami, Keisuke, et al.
Publicado: (2019)

BACH1 Binding Links the Genetic Risk for Severe Periodontitis with ST8SIA1
por: Chopra, A., et al.
Publicado: (2021)

ST8SIA6-AS1 Promotes the Epithelial-to-Mesenchymal Transition and Angiogenesis of Pituitary Adenoma
por: Li, Zuowei, et al.
Publicado: (2022)

Impact of structural aberrancy of polysialic acid and its synthetic enzyme ST8SIA2 in schizophrenia
por: Sato, Chihiro, et al.
Publicado: (2013)

The association between ST8SIA2 gene and behavioral phenotypes in children with autism spectrum disorder
por: Yang, Xiaolei, et al.
Publicado: (2022)

Identification and Functional Characterization of ST3GAL5 and ST8SIA1 Variants in Patients with Thyroid-Associated Ophthalmopathy
por: Park, Hyo Jin, et al.
Publicado: (2017)

Marine Bacterial Sialyltransferases
por: Yamamoto, Takeshi
Publicado: (2010)

Integrated analysis of multiple transcriptomic data identifies ST8SIA6‑AS1 and LINC01093 as potential biomarkers in HBV‑associated liver cancer
por: Xue, Jianhua, et al.
Publicado: (2023)

Association between ST8SIA2 and the Risk of Schizophrenia and Bipolar I Disorder across Diagnostic Boundaries
por: Yang, So Yung, et al.
Publicado: (2015)

St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity
por: Zhang, Pu, et al.
Publicado: (2021)

Compromised mammillary body connectivity and psychotic symptoms in mice with di- and mesencephalic ablation of ST8SIA2
por: Küçükerden, Melike, et al.
Publicado: (2022)

Sialyltransferase ST6GAL-1 mediates resistance to chemoradiation in rectal cancer
por: Smithson, Mary, et al.
Publicado: (2022)

Functional roles of ST8SIA3-mediated sialylation of striatal dopamine D(2) and adenosine A(2A) receptors
por: Lin, Chien-Yu, et al.
Publicado: (2019)

miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4
por: Fu, Wan, et al.
Publicado: (2021)

A New Assay for Determining Ganglioside Sialyltransferase Activities Lactosylceramide-2,3-Sialyltransferase (SAT I) and Monosialylganglioside-2,3-Sialyltransferase (SAT IV)
por: Sun, Cynthia Q., et al.
Publicado: (2014)

Characterisation of Genetic Variation in ST8SIA2 and Its Interaction Region in NCAM1 in Patients with Bipolar Disorder
por: Shaw, Alex D., et al.
Publicado: (2014)

Altered developmental neuroplasticity due to polysialyltransferase ST8SiaII deficiency in mice leads to schizophrenia-like phenotype
por: Zharkovsky, Alexander
Publicado: (2015)

Upregulation of miR-181c inhibits chemoresistance by targeting ST8SIA4 in chronic myelocytic leukemia
por: Zhao, Lifen, et al.
Publicado: (2016)

Lower promoter activity of the ST8SIA2 gene has been favored in evolving human collective brains
por: Hayakawa, Toshiyuki, et al.
Publicado: (2021)

Expression of active human sialyltransferase ST6GalNAcI in Escherichia coli
por: Skretas, Georgios, et al.
Publicado: (2009)

ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines
por: Videira, Paula A, et al.
Publicado: (2009)

ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells
por: Schultz, Matthew J, et al.
Publicado: (2013)

Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness
por: Hait, Nitai C., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rdeil1pov9ejnon9hg8ivqrtm2