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Current Nanoparticle-Based Technologies for Osteoarthritis Therapy

Osteoarthritis (OA) is a common chronic joint disease that is characterized by joint pain and stiffness, and limitation of motion and the major cause of disability, which reduces life quality of patients and brings a large economic burden to the family and society. Current clinical treatment is most...

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Detalles Bibliográficos
Autor principal: Jin, Guang-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760945/
https://www.ncbi.nlm.nih.gov/pubmed/33260493
http://dx.doi.org/10.3390/nano10122368
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author Jin, Guang-Zhen
author_facet Jin, Guang-Zhen
author_sort Jin, Guang-Zhen
collection PubMed
description Osteoarthritis (OA) is a common chronic joint disease that is characterized by joint pain and stiffness, and limitation of motion and the major cause of disability, which reduces life quality of patients and brings a large economic burden to the family and society. Current clinical treatment is mostly limited to symptomatic treatment aimed at pain alleviation and functional improvement, rather than suppressing the progression of OA. Nanotechnology is a promising strategy for the treatment of OA. In this review, we summarize the current experimental progress that focuses on technologies such as liposomes, micelles, dendrimers, polymeric nanoparticles (PNPs), exosomes, and inorganic nanoparticles (NPs) for their potential treatment of OA.
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spelling pubmed-77609452020-12-26 Current Nanoparticle-Based Technologies for Osteoarthritis Therapy Jin, Guang-Zhen Nanomaterials (Basel) Review Osteoarthritis (OA) is a common chronic joint disease that is characterized by joint pain and stiffness, and limitation of motion and the major cause of disability, which reduces life quality of patients and brings a large economic burden to the family and society. Current clinical treatment is mostly limited to symptomatic treatment aimed at pain alleviation and functional improvement, rather than suppressing the progression of OA. Nanotechnology is a promising strategy for the treatment of OA. In this review, we summarize the current experimental progress that focuses on technologies such as liposomes, micelles, dendrimers, polymeric nanoparticles (PNPs), exosomes, and inorganic nanoparticles (NPs) for their potential treatment of OA. MDPI 2020-11-28 /pmc/articles/PMC7760945/ /pubmed/33260493 http://dx.doi.org/10.3390/nano10122368 Text en © 2020 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Jin, Guang-Zhen
Current Nanoparticle-Based Technologies for Osteoarthritis Therapy
title Current Nanoparticle-Based Technologies for Osteoarthritis Therapy
title_full Current Nanoparticle-Based Technologies for Osteoarthritis Therapy
title_fullStr Current Nanoparticle-Based Technologies for Osteoarthritis Therapy
title_full_unstemmed Current Nanoparticle-Based Technologies for Osteoarthritis Therapy
title_short Current Nanoparticle-Based Technologies for Osteoarthritis Therapy
title_sort current nanoparticle-based technologies for osteoarthritis therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760945/
https://www.ncbi.nlm.nih.gov/pubmed/33260493
http://dx.doi.org/10.3390/nano10122368
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