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Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles

This paper presents a novel method to prevent blockages by embolic microspheres in catheter channels by using convex air bubbles attached to the channels’ inner wall surface. The clogging by microspheres can occur by the arching of the microspheres in the catheter. A few studies have been done on re...

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Autores principales: Park, Dong Hyeok, Jung, Yeun Jung, Steve Jeo Kins, Sandoz John Kinson, Kim, Young Deok, Go, Jeung Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760967/
https://www.ncbi.nlm.nih.gov/pubmed/33260919
http://dx.doi.org/10.3390/mi11121040
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author Park, Dong Hyeok
Jung, Yeun Jung
Steve Jeo Kins, Sandoz John Kinson
Kim, Young Deok
Go, Jeung Sang
author_facet Park, Dong Hyeok
Jung, Yeun Jung
Steve Jeo Kins, Sandoz John Kinson
Kim, Young Deok
Go, Jeung Sang
author_sort Park, Dong Hyeok
collection PubMed
description This paper presents a novel method to prevent blockages by embolic microspheres in catheter channels by using convex air bubbles attached to the channels’ inner wall surface. The clogging by microspheres can occur by the arching of the microspheres in the catheter. A few studies have been done on reducing the blockage, but their methods are not suitable for use with embolic catheters. In this study, straight catheter channels were fabricated. They had cavities to form convex air bubbles; additionally, a straight channel without the cavities was designed for comparison. Blockage was observed in the straight channel without the cavities, and the blockage arching angle was measured to be 70°, while no blockage occurred in the cavity channel with air bubbles, even at a geometrical arching angle of 85°. The convex air bubbles have an important role in preventing blockages by microspheres. The slip effect on the air bubble surface and the centrifugal effect make the microspheres drift away from the channel wall. It was observed that as the size of the cavity was increased, the drift distance became larger. Additionally, as more convex air bubbles were formed, the amount of early drift to the center increased. It will be advantageous to design a catheter with large cavities that have a small interval between them.
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spelling pubmed-77609672020-12-26 Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles Park, Dong Hyeok Jung, Yeun Jung Steve Jeo Kins, Sandoz John Kinson Kim, Young Deok Go, Jeung Sang Micromachines (Basel) Article This paper presents a novel method to prevent blockages by embolic microspheres in catheter channels by using convex air bubbles attached to the channels’ inner wall surface. The clogging by microspheres can occur by the arching of the microspheres in the catheter. A few studies have been done on reducing the blockage, but their methods are not suitable for use with embolic catheters. In this study, straight catheter channels were fabricated. They had cavities to form convex air bubbles; additionally, a straight channel without the cavities was designed for comparison. Blockage was observed in the straight channel without the cavities, and the blockage arching angle was measured to be 70°, while no blockage occurred in the cavity channel with air bubbles, even at a geometrical arching angle of 85°. The convex air bubbles have an important role in preventing blockages by microspheres. The slip effect on the air bubble surface and the centrifugal effect make the microspheres drift away from the channel wall. It was observed that as the size of the cavity was increased, the drift distance became larger. Additionally, as more convex air bubbles were formed, the amount of early drift to the center increased. It will be advantageous to design a catheter with large cavities that have a small interval between them. MDPI 2020-11-27 /pmc/articles/PMC7760967/ /pubmed/33260919 http://dx.doi.org/10.3390/mi11121040 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Park, Dong Hyeok
Jung, Yeun Jung
Steve Jeo Kins, Sandoz John Kinson
Kim, Young Deok
Go, Jeung Sang
Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles
title Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles
title_full Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles
title_fullStr Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles
title_full_unstemmed Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles
title_short Prevention of Microsphere Blockage in Catheter Tubes Using Convex Air Bubbles
title_sort prevention of microsphere blockage in catheter tubes using convex air bubbles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760967/
https://www.ncbi.nlm.nih.gov/pubmed/33260919
http://dx.doi.org/10.3390/mi11121040
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