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B-ALL Complexity: Is Targeted Therapy Still A Valuable Approach for Pediatric Patients?

SIMPLE SUMMARY: B-ALL is the more frequent childhood malignancy. Even though significant improvements in patients’ survival, some pediatric B-ALL have still poor prognosis and novel strategies are needed. Recently, new genetic abnormalities and altered signaling pathways have been described, definin...

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Detalles Bibliográficos
Autores principales: Ratti, Stefano, Lonetti, Annalisa, Follo, Matilde Y., Paganelli, Francesca, Martelli, Alberto M., Chiarini, Francesca, Evangelisti, Camilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7760974/
https://www.ncbi.nlm.nih.gov/pubmed/33255367
http://dx.doi.org/10.3390/cancers12123498