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Genetic Attenuation of Paraoxonase 1 Activity Induces Proatherogenic Changes in Plasma Proteomes of Mice and Humans

High-density lipoprotein (HDL), in addition to promoting reverse cholesterol transport, possesses anti-inflammatory, antioxidative, and antithrombotic activities. Paraoxonase 1 (PON1), carried on HDL in the blood, can contribute to these antiatherogenic activities. The PON1-Q192R polymorphism involv...

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Detalles Bibliográficos
Autores principales:	Sikora, Marta, Bretes, Ewa, Perła-Kaján, Joanna, Lewandowska, Izabela, Marczak, Łukasz, Jakubowski, Hieronim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761039/ https://www.ncbi.nlm.nih.gov/pubmed/33260536 http://dx.doi.org/10.3390/antiox9121198

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