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Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies
SIMPLE SUMMARY: Glioblastoma (GBM) is an incurable disease with a 14-month average life-expectancy following diagnosis, and clinical management has not improved in four decades. GBM mortality is due to rapid tumour growth and invasion into surrounding normal brain. Invasive cells make complete surgi...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761123/ https://www.ncbi.nlm.nih.gov/pubmed/33256106 http://dx.doi.org/10.3390/cancers12123531 |