Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies

SIMPLE SUMMARY: Glioblastoma (GBM) is an incurable disease with a 14-month average life-expectancy following diagnosis, and clinical management has not improved in four decades. GBM mortality is due to rapid tumour growth and invasion into surrounding normal brain. Invasive cells make complete surgi...

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Detalles Bibliográficos
Autores principales: Connor, Kate, Murray, David W., Jarzabek, Monika A., Tran, Nhan L., White, Kieron, Dicker, Patrick, Sweeney, Kieron J., O’Halloran, Philip J., MacCarthy, Brian, Shiels, Liam P., Lodi, Francesca, Lambrechts, Diether, Sarkaria, Jann N., Schiffelers, Raymond M., Symons, Marc, Byrne, Annette T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761123/
https://www.ncbi.nlm.nih.gov/pubmed/33256106
http://dx.doi.org/10.3390/cancers12123531

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