Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination

Demyelinated lesions in human pons observed after osmotic shifts in serum have been referred to as central pontine myelinolysis (CPM). Astrocytic damage, which is prominent in neuroinflammatory diseases like neuromyelitis optica (NMO) and multiple sclerosis (MS), is considered the primary event duri...

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Detalles Bibliográficos
Autores principales: Lohrberg, Melanie, Winkler, Anne, Franz, Jonas, van der Meer, Franziska, Ruhwedel, Torben, Sirmpilatze, Nikoloz, Dadarwal, Rakshit, Handwerker, Ronja, Esser, Daniel, Wiegand, Kerstin, Hagel, Christian, Gocht, Andreas, König, Fatima Barbara, Boretius, Susann, Möbius, Wiebke, Stadelmann, Christine, Barrantes-Freer, Alonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761156/
https://www.ncbi.nlm.nih.gov/pubmed/33357244
http://dx.doi.org/10.1186/s40478-020-01105-2

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