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Targeted Protein Degradation Tools: Overview and Future Perspectives

SIMPLE SUMMARY: Gene inactivation is a powerful strategy to study the function of specific proteins in the context of cellular physiology that can be applied for only non-essential genes since their DNA sequence is destroyed. On the other hand, perturbing the amount of the transcript can lead to inc...

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Detalles Bibliográficos
Autores principales:	Prozzillo, Yuri, Fattorini, Gaia, Santopietro, Maria Virginia, Suglia, Luigi, Ruggiero, Alessandra, Ferreri, Diego, Messina, Giovanni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761331/ https://www.ncbi.nlm.nih.gov/pubmed/33256092 http://dx.doi.org/10.3390/biology9120421

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