Isoform- and Paralog-Switching in IR-Signaling: When Diabetes Opens the Gates to Cancer

Insulin receptor (IR) and IR-related signaling defects have been shown to trigger insulin-resistance in insulin-dependent cells and ultimately to give rise to type 2 diabetes in mammalian organisms. IR expression is ubiquitous in mammalian tissues, and its over-expression is also a common finding in...

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Detalles Bibliográficos
Autores principales: Scalia, Pierluigi, Giordano, Antonio, Martini, Caroline, Williams, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761347/
https://www.ncbi.nlm.nih.gov/pubmed/33266015
http://dx.doi.org/10.3390/biom10121617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761347/
https://www.ncbi.nlm.nih.gov/pubmed/33266015
http://dx.doi.org/10.3390/biom10121617

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