Cargando…
Isoform- and Paralog-Switching in IR-Signaling: When Diabetes Opens the Gates to Cancer
Insulin receptor (IR) and IR-related signaling defects have been shown to trigger insulin-resistance in insulin-dependent cells and ultimately to give rise to type 2 diabetes in mammalian organisms. IR expression is ubiquitous in mammalian tissues, and its over-expression is also a common finding in...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761347/ https://www.ncbi.nlm.nih.gov/pubmed/33266015 http://dx.doi.org/10.3390/biom10121617 |