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Histone Carbonylation Is a Redox-Regulated Epigenomic Mark That Accumulates with Obesity and Aging
Oxidative stress is a hallmark of metabolic disease, though the mechanisms that define this link are not fully understood. Irreversible modification of proteins by reactive lipid aldehydes (protein carbonylation) is a major consequence of oxidative stress in adipose tissue and the substrates and spe...
Autores principales: | Hauck, Amy K., Zhou, Tong, Upadhyay, Ambuj, Sun, Yuxiang, O’Connor, Michael B., Chen, Yue, Bernlohr, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761391/ https://www.ncbi.nlm.nih.gov/pubmed/33271806 http://dx.doi.org/10.3390/antiox9121210 |
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