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Histone Carbonylation Is a Redox-Regulated Epigenomic Mark That Accumulates with Obesity and Aging

Oxidative stress is a hallmark of metabolic disease, though the mechanisms that define this link are not fully understood. Irreversible modification of proteins by reactive lipid aldehydes (protein carbonylation) is a major consequence of oxidative stress in adipose tissue and the substrates and spe...

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Detalles Bibliográficos
Autores principales: Hauck, Amy K., Zhou, Tong, Upadhyay, Ambuj, Sun, Yuxiang, O’Connor, Michael B., Chen, Yue, Bernlohr, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761391/
https://www.ncbi.nlm.nih.gov/pubmed/33271806
http://dx.doi.org/10.3390/antiox9121210

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