BCS Class IV Oral Drugs and Absorption Windows: Regional-Dependent Intestinal Permeability of Furosemide

Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class. While solubility is often predictable, intestinal permeability is rather complicated and highly dependent on m...

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Detalles Bibliográficos
Autores principales: Markovic, Milica, Zur, Moran, Ragatsky, Inna, Cvijić, Sandra, Dahan, Arik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761534/
https://www.ncbi.nlm.nih.gov/pubmed/33276565
http://dx.doi.org/10.3390/pharmaceutics12121175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761534/
https://www.ncbi.nlm.nih.gov/pubmed/33276565
http://dx.doi.org/10.3390/pharmaceutics12121175

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