Modelling of Immune Checkpoint Network Explains Synergistic Effects of Combined Immune Checkpoint Inhibitor Therapy and the Impact of Cytokines in Patient Response

SIMPLE SUMMARY: The future of cancer immunotherapy relies on a combination of individually targeted therapies. However, a lot of experiments are needed to define the most effective combinations of drugs. A computational and modelling approach could help reduce the number of experiments and suggest o...

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Detalles Bibliográficos
Autores principales: Kondratova, Maria, Barillot, Emmanuel, Zinovyev, Andrei, Calzone, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761568/
https://www.ncbi.nlm.nih.gov/pubmed/33276543
http://dx.doi.org/10.3390/cancers12123600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761568/
https://www.ncbi.nlm.nih.gov/pubmed/33276543
http://dx.doi.org/10.3390/cancers12123600

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