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Leucine Supplementation Decreases HDAC4 Expression and Nuclear Localization in Skeletal Muscle Fiber of Rats Submitted to Hindlimb Immobilization

In this study we surveyed a rat skeletal muscle RNA-Seq for genes that are induced by hindlimb immobilization and, in turn, become attenuated by leucine supplementation. This approach, in search of leucine-atrophy protection mediating genes, identified histone deacetylase 4 (HDAC4) as highly respons...

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Detalles Bibliográficos
Autores principales:	Alves, Paula K. N., Cruz, André, Silva, William J., Labeit, Siegfried, Moriscot, Anselmo S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7761616/ https://www.ncbi.nlm.nih.gov/pubmed/33276563 http://dx.doi.org/10.3390/cells9122582

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